Rabbit Anti Human CRHR1 Antibody-FITC
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Catalog numberCSB-PA005965YC01HU_50ug
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PricePlease ask
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Size50ug
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Long nameRabbit Antibody against Human CRHR1, FITC
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Synonym nameCRHR1 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA
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ConjugationFITC
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Antibody isotypeIgG
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UniProt IDP34998
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FormatLiquid, diluted in buffer
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Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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Purity>95%
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Purification methodProtein G purified
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human Corticotropin-releasing factor receptor 1 protein (24-121AA)
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Immunogen speciesHuman
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AliasCRF-R-1,CRF-R1,CRFR-1,Corticotropin-releasing hormone receptor 1,CRH-R-1,CRH-R1,CRHR1,CRFR, CRFR1, CRHR
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BackgroundG-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
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ClonalityPolyclonal antibody
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Shipping and storageCRHR1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Cusabio Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Cusabio FITC is highly sensitive to pH extremes. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional conjugationAnti-FITC Antibody
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolLINC02210-CRHR1, CRHR1, LINC02210
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Short nameAnti-CRHR1
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Techniqueanti human, Antibody, Rabbit, anti, FITC, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, Fluorescein
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HostRabbit, Rabbits
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LabelFITC
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SpeciesHuman, Humans
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Alternative nameCRHR1 Antibody,FITC conjugated
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Alternative techniqueantibodies, rabbit-anti, fluorescine
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Gene info
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Identity
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Gene
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Long gene nameLINC02210-CRHR1 readthrough
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Locus
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Discovery year2017-02-01
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Entrez gene record
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene namecorticotropin releasing hormone receptor 1
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-12-13
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Entrez gene record
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Pubmed identfication
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Classification
- Corticotropin releasing hormone receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelong intergenic non-protein coding RNA 2210
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Synonyms gene
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Synonyms gene name
- chromosome 17 open reading frame 69
- CRHR1 intronic transcript 1 (non-protein coding)
- CRHR1 intronic transcript 1
- LINC.tmp695175
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-12-16
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Entrez gene record
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RefSeq identity
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Classification
- Long intergenic non-protein coding RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
