CD79B, human recombinant
-
Catalog number7318-50
-
PricePlease ask
-
Size50 ug
-
-
SynonymsCD79b molecule, immunoglobulin-associated beta, AGM6, B29, IGB
-
Alternative_namesCD79b molecule, immunoglobulin-associated beta, AGM6, B29, IGB
-
DescriptionRequired for BCR-mediated signaling
-
RecombinantYes
-
SourceE. coli
-
Purity by SDS PAGE≥90%
-
AssaySDS-PAGE
-
Endotoxin Level< 1.0 EU per 1 microgram of protein
-
Molecular Weight17.7 kDa (155 aa, 29-159 aa + His tag), confirmed by MALDI-TOF.
-
Storage Temp-80°C
-
ShippingDry Ice
-
Shelf Life12 months
-
Concentration1 mg/ml
-
AppearanceLiquid
-
Physical form description1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea and 10% glycerol.
-
Background InformationCD79B, also known as Igb and B29, is a 36 kDa transmembrane glycoprotein in the immunoglobulin superfamily. Heterodimers of CD79A and CD79B associate with a membrane bound immunoglobulin on the B cell surface to form the B cell antigen receptor complex (BCR). CD79A and CD79B are required for BCR-mediated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B protein, fused to His-tag at N-terminus, was expressed in E.coli.
-
Amino acid sequenceMGSSHHHHHH SSGLVPRGSH MGSMARSEDR YRNPKGSACS RIWQSPRFIA RKRGFTVKMH CYMNSASGNV SWLWKQEMDE NPQQLKLEKG RMEESQNESL ATLTIQGIRF EDNGIYFCQQ KCNNTSEVYQ GCGTELRVMG FSTLAQLKQR NTLKD
-
HandlingCentrifuge the vial prior to opening.
-
UsageFor Research Use Only! Not to be used in humans
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Additional sourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolCD79B
-
Short nameCD79B, recombinant
-
TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
SpeciesHuman, Humans
-
Alternative nameCD79b molecule, immunoglobulin-associated b, H. sapiens Rec.
-
Alternative techniquerec
-
Alternative to gene targetCD79b molecule, immunoglobulin-associated beta, AGM6 and B29 and IGB, CD79B and IDBG-64384 and ENSG00000007312 and 974, protein binding, nuclei, Cd79b and IDBG-213455 and ENSMUSG00000040592 and 15985, CD79B and IDBG-641775 and ENSBTAG00000044204 and 509801
-
Gene info
-
Identity
-
Gene
-
Long gene nameCD79b molecule
-
Synonyms gene
-
Synonyms gene name
- CD79B antigen (immunoglobulin-associated beta)
- CD79b molecule, immunoglobulin-associated beta
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1992-08-04
-
Entrez gene record
-
Pubmed identfication
-
Classification
- V-set domain containing
- CD molecules
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data