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Rabbit Anti Human Chk2 pThr383 Polyclonal

Rabbit Anti Human Chk2 pThr383 Polyclonal is available 18 times from Stressmark antibodies labs

SPC-950D-ALP | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: Alkaline Phosphatase size: 100 µl | 440.62 USD

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SPC-950D-APC | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: APC size: 100 µl | 446.25 USD

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SPC-950D-A390 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: ATTO 390 size: 100 µl | 448.51 USD

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SPC-950D-A488 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: ATTO 488 size: 100 µl | 447.38 USD

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SPC-950D-A565 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: ATTO 565 size: 100 µl | 447.38 USD

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SPC-950D-A594 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: ATTO 594 size: 100 µl | 447.38 USD

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SPC-950D-A633 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: ATTO 633 size: 100 µl | 447.38 USD

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SPC-950D-A655 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: ATTO 655 size: 100 µl | 447.38 USD

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SPC-950D-A680 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: ATTO 680 size: 100 µl | 447.38 USD

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SPC-950D-A700 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: ATTO 700 size: 100 µl | 447.38 USD

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SPC-950D-BI | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: Biotin size: 100 µl | 442.87 USD

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SPC-950D-FITC | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: FITC size: 100 µl | 438.36 USD

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SPC-950D-HRP | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: HRP size: 100 µl | 433.86 USD

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SPC-950D-P594 | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: PE/ATTO 594 size: 100 µl | 455.27 USD

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SPC-950D-PCP | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: PerCP size: 100 µl | 446.25 USD

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SPC-950D-RPE | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: RPE size: 100 µl | 444.00 USD

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SPC-950D-STR | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: Streptavidin size: 100 µl | 445.13 USD

Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Test StressMark antibodies supplies antibodies that are for research of human proteins.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name Oryctolagus cuniculus
Gene targetChk2 pThr383 Streptavidin
Short name Rabbit Anti- Chk2 (pThr383) Polyclonal: Streptavidin
Technique anti-Human, Polyclonal, Rabbit, anti
Label streptavidin
Alternative name production species: rabbit antibody to-H. sapiens Chk2 (pThr383) polyclonal: biotinilated-binding streptavidin
MeSH Data
Name Blotting, Western
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Product images
    #Human#.jpg

SPC-950D | Rabbit Anti-Human Chk2 (pThr383) Polyclonal: Unconjugated size: 100 µl | 393.29 USD

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PubMed number Refer to PubMed
Net weight (g) 0.1
Recommended buffer for storage PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Antibody's reactivity Human
Warning information Non-hazardous
Raised in Rabbit
NCBI number NP_009125
Gene number 11200
Released date 29/Aug/2016
Immunogen A phospho-specific peptide corresponding to residues surrounding Thr383 of human Chk2 (AA380-386)
Antibody's other name Cds1 homolog Antibody, Checkpoint kinase 2 Antibody, CHEK 2 Antibody, CHK2 checkpoint homolog Antibody, CHK2_HUMAN Antibody, hCds1 Antibody, LFS 2 Antibody, PP1425 Antibody, RAD 53 Antibody, Serine/threonine protein kinase Chk2 Antibody
Protein number O96017
Antibody's recommended dilutions for use WB (1:250); optimal dilutions for assays should be determined by the user.
Tested applications To be tested
Antibody's datasheet Contact our support service to receive datasheet or other technical documentation.
Total weight (kg) 1.4
Stock availabilit In Stock
Scientific context Chk2 is a protein kinase involved in cell cycle arrest in response to DNA damage. CHK2 is activated through phosphorylation by ATM and ATR at T68. Activated CHK2 phosphorylates and inhibits CDC25 a dual-specificity phosphatase required for progression through the cell cycle. CHK2 further causes cell cycle earrest through activation of a DNA repair protein BRCA1 and apoptosis factor PML. The role of CHK2 in the development of cancer is in a primarily tumour suppressor role through causing cell cycle arrest. It has been observed that inhibition of CHK2 through mutations in the regulatory FHA domain has been observed in low frequency in osteosarcomas and cancers of the ovary, lung and vulva. Another mutation, "1100delC" has been commonly found in breast cancers.
Antibody's target Human Chk2 (pThr383)
Certificate of analysis A 1:250 dilution of SPC-950 was sufficient for detection of Chk2 (pThr383) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Tissue specificity See included datasheet or contact our support service.
Antibody's full description Rabbit Anti-Human Chk2 (pThr383) Polyclonal
Country of production Canada
Antibody's purified from Peptide Affinity Purified
Antibody's concentration See included datasheet or contact our support service
Tested reactivity To be tested
Antibody in cell Nucleus
Antibody's category Polyclonal Antibodies
Representative figure link No Data Available
Bibliography Refer to PubMed
Verified applications WB, AM
Antibody's specificity Detects 60.915 kDa.
Storage recommendations -20°C
Shipping recommendations Blue Ice or 4°C
Host Rabbit
Species Human
Alternative technique polyclonals
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Rabbit Anti-Human Chk2 (pThr383) Polyclonal: Streptavidin
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  • Chk2
  • pThr383
  • Alkaline
  • Phosphatase
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