HPV L2 Antibody
-
Catalog numberbs-8547R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameHPV L2 Primary Polyclonal Antibody
-
Also known asHPV L2 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenHPV L2
-
SpecificityThis is a highly specific antibody against HPV L2. This antibody may detect Minor capsid protein L2 in HPV16, HPV31, HPV35, HPV43, HPV11
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range1-50/473
-
Subcellular locationNucleus
-
SourceKLH conjugated synthetic peptide derived from HPV16 L2
-
Gene ID number1489081
-
Swiss ProtP03107
-
Tested ApplicationsIHC-P, IF(IHC-P)
-
Recommended dilutionsIHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityVirus
-
Cross reactive species detailsHPV16
-
Background of the target antigenMinor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network. Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus. Mediates the viral genome import into the nucleus through binding to host importins. Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection. Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions. During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesMinor capsid protein L2; L2
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Short nameAnti-HPV L2
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameHPV L2 Polyclonal Antibody
-
Alternative techniqueantibodies
-
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data