SIGIRR (Single Ig IL-1-related Receptor, Single Ig IL-1R-related Molecule, Single Immunoglobulin Domain-containing IL1R-related Protein, Toll/IL-1 Receptor 8, TIR8, UNQ301/PRO342) (APC)

• Catalog number
  GEN609464
• Price
  Please ask
• Size
  100 Tests

• Also known as
  SIGIRR
• Other names
  single Ig IL-1-related receptor; Single Ig IL-1-related receptor; single Ig IL-1-related receptor; OTTHUMP00000229641; OTTHUMP00000229642; OTTHUMP00000229643; OTTHUMP00000229644; OTTHUMP00000229645; toll/interleukin-1 receptor 8; single Ig IL-1R-related molecule; single immunoglobulin domain IL1R1 related; single immunoglobulin domain-containing IL1R-related protein; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; Single Ig IL-1R-related molecule; Single immunoglobulin domain-containing IL1R-related protein; Toll/interleukin-1 receptor 8
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  SIGIRR; SIGIRR; TIR8; MGC110992; N/A
• Gene name synonims
  SIGIRR; SIGIRR; TIR8; MGC110992; N/A
• Other gene names
  SIGIRR; SIGIRR; TIR8; MGC110992; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a
• Clone
  10K61
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human SIGIRR.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
• Concentration
  N/A
• Storage and shipping
  May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Store the antibody at +4 degrees Celsius. as an undiluted liquid. Stable for 12 months. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
• Tested applications
  Flow Cytometry (FC/FACS)
• Gene
  The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
• Description
  Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  SIGIRR   Single   IL-1-related   Receptor   Single   IL-1R-related   Molecule   Single   Immunoglobulin   Domain   IL1R-related   Protein   Toll/IL-1   Receptor   TIR8   UNQ301/PRO342   APC  
• Gene symbol
  SIGIRR, IL1A, IL1B, IL1F10, IL36B, IL19, IL1RL2, IL36G, IL25, IL36A
• Short name
  SIGIRR (Single Ig IL-1- Receptor, Single Ig IL-1R- Molecule, Single Immunoglobulin Domain- IL1R- Protein, Toll/IL-1 Receptor 8, TIR8, UNQ301/PRO342) (APC)
• Label
  APC
• Alternative name
  Anti-SIGIRR (Single Ig IL-1-related Receptor, Single Ig IL-1R-related Molecule, Single Immunoglobulin Domain-containing IL1R-related Protein, Toll/Interleukin-1 Receptor 8, TIR8, UNQ301/PRO342) (APC)
• Alternative to gene target
  single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, SIGIRR and IDBG-16551 and ENSG00000185187 and 59307, protein binding, Plasma membranes, Sigirr and IDBG-211977 and ENSMUSG00000025494 and 24058, SIGIRR and IDBG-645604 and ENSBTAG00000011149 and 531801

Gene info

• Identity
  HGNC:30575
• Gene
  SIGIRR
• Long gene name
  single Ig and TIR domain containing
• Synonyms gene name
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
• Synonyms
  • TIR8
  • IL-1R8
• Synonyms name
  • single immunoglobulin domain IL1R1 related
• Locus
  11p15.5
• Discovery year
  2005-10-10
• Entrez gene record
  59307
• Pubmed identfication
  • 10346978
• RefSeq identity
  • NM_021805
• Classification
  • TIR domain containing
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000165412

Gene info

• Identity
  HGNC:5991
• Gene
  IL1A
• Long gene name
  interleukin 1 alpha
• Synonyms gene
  • IL1
• Synonyms
  • IL1F1
  • IL-1A
  • IL1-ALPHA
• Synonyms name
  • preinterleukin 1 alpha
  • hematopoietin-1
  • pro-interleukin-1-alpha
• GenBank acession
  • M28983
• Locus
  2q14.1
• Discovery year
  2001-06-22
• Entrez gene record
  3552
• Pubmed identfication
  • 8188271
  • 2989698
• RefSeq identity
  • NM_000575
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131315

Gene info

• Identity
  HGNC:5992
• Gene
  IL1B
• Long gene name
  interleukin 1 beta
• Synonyms
  • IL1F2
  • IL-1B
  • IL1-BETA
• GenBank acession
  • M15330
• Locus
  2q14.1
• Discovery year
  1989-03-31
• Entrez gene record
  3553
• Pubmed identfication
  • 2954882
  • 2989698
• RefSeq identity
  • NM_000576
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131344

Gene info

• Identity
  HGNC:15552
• Gene
  IL1F10
• Long gene name
  interleukin 1 family member 10
• Synonyms gene name
  • interleukin 1 family, member 10 (theta)
• Synonyms
  • FKSG75
  • IL-1HY2
  • IL-1F10
  • IL1-theta
  • MGC11983
  • MGC119832
  • MGC119833
• Synonyms name
  • FIL1- theta
  • interleukin-1 receptor antagonist FKSG75
• GenBank acession
  • AY026753
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  84639
• Pubmed identfication
  • 11747621
  • 11991723
  • 11991722
• RefSeq identity
  • NM_173161
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131339

Gene info

• Identity
  HGNC:15564
• Gene
  IL36B
• Long gene name
  interleukin 36 beta
• Synonyms gene
  • IL1F8
• Synonyms gene name
  • interleukin 1 family, member 8 (eta)
• Synonyms
  • FIL1
  • IL-1H2
  • IL-1F8
  • FILI-(ETA)
  • IL1-ETA
  • IL1H2
  • MGC126880
  • MGC126882
• GenBank acession
  • AF201833
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27177
• Pubmed identfication
  • 10625660
  • 10512743
  • 16646978
• RefSeq identity
  • NM_014438
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131338

Gene info

• Identity
  HGNC:5990
• Gene
  IL19
• Long gene name
  interleukin 19
• Synonyms
  • IL-19
  • MDA1
  • ZMDA1
  • IL-10C
  • NG.1
• Synonyms name
  • melanoma differentiation associated protein-like protein
• GenBank acession
  • AF192498
• Locus
  1q32.1
• Discovery year
  2000-03-29
• Entrez gene record
  29949
• Pubmed identfication
  • 11196675
• RefSeq identity
  • NM_153758
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000036387

Gene info

• Identity
  HGNC:5999
• Gene
  IL1RL2
• Long gene name
  interleukin 1 receptor like 2
• Synonyms
  • IL1R-rp2
  • IL1RRP2
• GenBank acession
  • U49065
• Locus
  2q12.1
• Discovery year
  1998-12-17
• Entrez gene record
  8808
• Pubmed identfication
  • 8898719
  • 10191101
  • 11466363
• RefSeq identity
  • NM_003854
• Classification
  • Immunoglobulin like domain containing
  • Interleukin receptors
  • TIR domain containing
• VEGA ID
  OTTHUMG00000130776

Gene info

• Identity
  HGNC:15741
• Gene
  IL36G
• Long gene name
  interleukin 36 gamma
• Synonyms gene
  • IL1F9
• Synonyms gene name
  • interleukin 1 family, member 9
• Synonyms
  • IL-1H1
  • IL-1RP2
  • IL-1F9
  • IL1H1
  • IL1E
• Synonyms name
  • interleukin-1 homolog 1
  • interleukin 1-related protein 2
  • interleukin-1 epsilon
• GenBank acession
  • AF200492
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  56300
• Pubmed identfication
  • 10860666
  • 10744718
  • 11991722
  • 11991723
• RefSeq identity
  • NM_019618
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131336

Gene info

• Identity
  HGNC:13765
• Gene
  IL25
• Long gene name
  interleukin 25
• Synonyms gene
  • IL17E
• Synonyms gene name
  • interleukin 17E
• Synonyms
  • IL-25
  • IL-17E
• GenBank acession
  • AF305200
• Locus
  14q11.2
• Discovery year
  2001-01-26
• Pubmed identfication
  • 11058597
  • 11754819
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000028749

Gene info

• Identity
  HGNC:15562
• Gene
  IL36A
• Long gene name
  interleukin 36 alpha
• Synonyms gene
  • IL1F6
• Synonyms gene name
  • interleukin 1 family, member 6 (epsilon)
• Synonyms
  • FIL1
  • FIL1E
  • IL-1F6
  • IL1(EPSILON)
  • MGC129553
  • MGC129552
• GenBank acession
  • AF201831
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27179
• Pubmed identfication
  • 10625660
• RefSeq identity
  • NM_014440
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000153320

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