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Other name
Recombining binding protein suppressor of hairless,CBF-1,J kappa-recombination signal-binding protein,RBP-J kappa,RBP-J,RBP-JK,Renal carcinoma antigen NY-REN-30,RBPJ,IGKJRB,IGKJRB1,RBPJK,RBPSUH
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Immunogen
Recombinant human Recombining binding protein suppressor of hairless protein (243-485AA)
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Verified reactivity
Human, Mouse
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Verified applications
ELISA,WB,IHC,IF. Recommended dilution:WB:1:2000-1:5000,IHC:1:20-1:200,IF:1:50-1:200
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Raised in
Rabbit
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Clonality
Polyclonal
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Protein number
Q06330
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Gene number
Please refer to GenBank
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NCBI number
Please refer to NCBI
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Purity
Protein G purified, >95%
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Storage recommendation
Aliquot and store at -20°C. Minimize freezing and thawing.
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Use before
1 year
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Shipping requirements
Blue ice
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Estimated production time
3-7 business days
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Supplementary information
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) (PubMed:23303788).
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Notes
For research use only. Not for diagnostic procedures.
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Properties
If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translation
anticorps
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Gene target
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Gene symbol
RBPJ
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Short name
RBPJ Polyclonal Antibody
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Technique
Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Label
Unconjugated
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Alternative name
recombination signal binding protein to measure immunoglobulin kappa J region polyclonal (antibody to-)
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Alternative technique
polyclonals, antibodies
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Alternative to gene target
recombination signal binding protein for immunoglobulin kappa J region, AOS3 and CBF1 and csl and IGKJRB and IGKJRB1 and KBF2 and RBP-J and RBPJK and RBPSUH and SUH, RBPJ and IDBG-12527 and ENSG00000168214 and 3516, protein N-terminus binding, nuclei, Rbpj and IDBG-164658 and ENSMUSG00000039191 and 19664, RBPJ and IDBG-641468 and ENSBTAG00000003602 and 767928
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