FGF-2/FGF-basic, bovine recombinant
-
Catalog number4040-1000
-
PricePlease ask
-
Size1 mg
-
-
SynonymsFGF-2, FGF2
-
Alternative_namesFGF2, HBGF-2, Prostatropin, Basic fibroblast growth factor, Heparin-binding growth factor 2
-
DescriptionA growth factor involved in angiogenesis, wound healing and embryonic development
-
RecombinantYes
-
SourceE. coli
-
Purity by SDS PAGE≥97%
-
AssaySDS-PAGE
-
Purity≥97%
-
Biological activityThe ED50, measured in a mitogenic assay using quiescent NR6R-3T3 fibroblasts was found to be
-
Molecular Weight17.25 kDa
-
Storage Temp-20°C
-
ShippingGel pack
-
Shelf Life12 months
-
AppearanceLyophilized protein
-
Physical form descriptionSterile filtered white lyophilized powder. Prepared fom a sterile solution containing 1 % HSA.
-
Reconstitution InstructionsReconstitute in sterile water to a concentration not less than 0.1 mg/ml. Aliquot and store at –20°C. Avoid freeze-thaw cycles.
-
Background InformationFGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. FGF-2 Bovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 155 amino acids and having a molecular mass of 17250 Dalton. The Fibroblast Growth Factor 2 is purified by proprietary chromatographic techniques. The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Ala-Gly-Ser.
-
HandlingCentrifuge the vial prior to opening.
-
UsageFor Research Use Only! Not to be used in humans
-
Additional descriptionBasic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.
-
Additional sourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolFGF18, FGF17, NUDT6, FGF2, FGF4, FGF1, FGF13, MIR1289-2, MIR521-2, MIR509-2
-
Short nameFGF-2/FGF- , recombinant
-
TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
SpeciesBovine, Bos Taurus genes are available form the Bovine Genome database.
-
Alternative nameFGF-2/FGF-basic, bovine Rec.
-
Alternative techniquerec
-
Gene info
-
Identity
-
Gene
-
Long gene namefibroblast growth factor 18
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-12-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fibroblast growth factor family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namefibroblast growth factor 17
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-12-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fibroblast growth factor family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namenudix hydrolase 6
-
Synonyms gene name
- nudix (nucleoside diphosphate linked moiety X)-type motif 6
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-09-03
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Nudix hydrolase family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namefibroblast growth factor 2
-
Synonyms gene
-
Synonyms gene name
- fibroblast growth factor 2 (basic)
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fibroblast growth factor family
- Receptor ligands
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene namefibroblast growth factor 4
-
Synonyms gene
-
Synonyms gene name
- heparin secretory transforming protein 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1988-04-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fibroblast growth factor family
- Receptor ligands
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namefibroblast growth factor 1
-
Synonyms gene
-
Synonyms gene name
- fibroblast growth factor 1 (acidic)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fibroblast growth factor family
- Receptor ligands
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namefibroblast growth factor 13
-
Synonyms gene
-
Synonyms gene name
- long intergenic non-protein coding RNA 889
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1996-12-16
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Fibroblast growth factor family
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1289-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1289 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 521-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR515 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 509-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2007-10-24
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR506 family
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
