Recombinant Human Suppressor of cytokine signaling 1 (SOCS1)

  • Catalog number
    RPC24961-1mg
  • Price
    Please ask
  • Size
    1mg
  • Estimated Turnaround Time
    6-11 business days
  • Gene Name
    SOCS1
  • Alternative Names
    JAK-binding protein; JABSTAT-induced STAT inhibitor 1; SSI-1Tec-interacting protein 3; TIP-3
  • Source
    Yeast
  • Purity
    > 90% by SDS-PAGE
  • Shipping Conditions
    Ice packs
  • Storage conditions
    Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
  • Shelf life
    12 months in lyophilized form; 6 months in solution form.
  • Restriction
    For research use only. Not for diagnostic procedures.
  • Description
    Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    SOCS1
  • Short name
    Recombinant Suppressor of cytokine signaling 1 (SOCS1)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Homo sapiens (Human), Humans
  • Alternative name
    Rec. H. sapiens Suppressor on cytokine signaling 1 (suppressor on cytokine signaling 1)
  • Alternative technique
    rec
  • Alternative to gene target
    suppressor of cytokine signaling 1, CIS1 and CISH1 and JAB and SOCS-1 and SSI-1 and SSI1 and TIP3, SOCS1 and IDBG-14621 and ENSG00000185338 and 8651, protein kinase binding, nuclei, Socs1 and IDBG-132667 and ENSMUSG00000038037 and 12703, SOCS1 and IDBG-648701 and ENSBTAG00000004386 and 518795
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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