Soluble Receptor Activator of NF-Kappa B (sRANK Ligand) Anti-Human

• Catalog number
  K0112877
• Price
  Please ask
• Size
  1X50ug

• Data Sheet URL
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Test
  Koma Biotech supplies antibodies that are for research of human proteins.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Soluble   Receptor   Activator   NF-Kappa   sRANK   Ligand  
• Gene symbol
  NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFYC, NFATC2, NFIL3
• Short name
  Soluble Receptor Activator of NF-Kappa B (sRANK Ligand) Anti-
• Technique
  anti-Human, anti-, anti, antibody to, antibodies, antibodies against human proteins
• Species
  Human, Humans
• Alternative name
  Soluble Receptor Activator on NF-Kappa B (sRANK Ligand) Antibody toHuman
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29902
• Gene
  NFE4
• Long gene name
  nuclear factor, erythroid 4
• Synonyms
  • NF-E4
• Locus
  7q22.1
• Discovery year
  2013-08-23
• Entrez gene record
  58160
• Pubmed identfication
  • 11003662
• RefSeq identity
  • NR_166510
• VEGA ID
  OTTHUMG00000157208

Gene info

• Identity
  HGNC:7780
• Gene
  NFE2
• Long gene name
  nuclear factor, erythroid 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
• Synonyms
  • NF-E2
• GenBank acession
  • BC005044
• Locus
  12q13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4778
• Pubmed identfication
  • 8355703
• RefSeq identity
  • NM_006163
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000169761

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

Gene info

• Identity
  HGNC:6057
• Gene
  INA
• Long gene name
  internexin neuronal intermediate filament protein alpha
• Synonyms gene
  • NEF5
• Synonyms gene name
  • internexin neuronal intermediate filament protein, alpha
• Synonyms
  • NF-66
• GenBank acession
  • S78296
• Locus
  10q24.33
• Discovery year
  1999-03-24
• Entrez gene record
  9118
• Pubmed identfication
  • 7769995
• RefSeq identity
  • NM_032727
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000018986

Gene info

• Identity
  HGNC:29866
• Gene
  NFASC
• Long gene name
  neurofascin
• Synonyms gene name
  • neurofascin homolog (chicken)
• Synonyms
  • NRCAML
  • KIAA0756
  • FLJ46866
  • NF
• GenBank acession
  • AK027553
• Locus
  1q32.1
• Discovery year
  2005-11-22
• Entrez gene record
  23114
• Pubmed identfication
  • 1377696
  • 8672144
• RefSeq identity
  • NM_001005388
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000151697

Gene info

• Identity
  HGNC:7775
• Gene
  NFATC1
• Long gene name
  nuclear factor of activated T cells 1
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • nuclear factor of activated T-cells 1
• Synonyms
  • NF-ATC
  • NFATc
  • NFAT2
• GenBank acession
  • U08015
• Locus
  18q23
• Discovery year
  1994-11-16
• Entrez gene record
  4772
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_172390
• Classification
  • Nuclear factors of activated T-cells
  • IPT domain containing
• VEGA ID
  OTTHUMG00000132897

Gene info

• Identity
  HGNC:7806
• Gene
  NFYC
• Long gene name
  nuclear transcription factor Y subunit gamma
• Synonyms gene name
  • nuclear transcription factor Y, gamma
• Synonyms
  • CBF-C
  • NF-YC
• GenBank acession
  • U78774
• Locus
  1p34.2
• Discovery year
  1996-10-26
• Entrez gene record
  4802
• Pubmed identfication
  • 8921405
  • 9249075
• RefSeq identity
  • NM_014223
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000007729

Gene info

• Identity
  HGNC:7776
• Gene
  NFATC2
• Long gene name
  nuclear factor of activated T cells 2
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • nuclear factor of activated T-cells 2
• Synonyms
  • NF-ATP
  • NFATp
  • NFAT1
• GenBank acession
  • U43342
  • U43341
• Locus
  20q13.2
• Discovery year
  1994-11-16
• Entrez gene record
  4773
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_012340
• Classification
  • IPT domain containing
  • Nuclear factors of activated T-cells
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000032747

Gene info

• Identity
  HGNC:7787
• Gene
  NFIL3
• Long gene name
  nuclear factor, interleukin 3 regulated
• Synonyms gene
  • IL3BP1
• Synonyms gene name
  • interleukin-3 binding protein 1
• Synonyms
  • E4BP4
  • NFIL3A
  • NF-IL3A
• Synonyms name
  • E4 promoter-binding protein
  • adenovirus E4 promoter region binding protein
• GenBank acession
  • X64318
• Locus
  9q22.31
• Discovery year
  1995-02-13
• Entrez gene record
  4783
• Pubmed identfication
  • 7565758
  • 1620116
• RefSeq identity
  • NM_005384
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000020209

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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