EMAP II, human recombinant
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Catalog number4463-1000
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PricePlease ask
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Size1 mg
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SynonymsAIMP1, EMAP2, EMAP-2, EMAPII, SCYE1, Multisynthetase complex auxiliary component p43, Endothelial monocyte-activating polypeptide 2, EMAP-II, p43,
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Alternative_namesAIMP1, EMAP2, EMAP-2, EMAPII, SCYE1, Multisynthetase complex auxiliary component p43, Endothelial monocyte-activating polypeptide 2, EMAP-II, p43,
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DescriptionA proinflammatory cytokine chemotactic for monocytes and granulocytes
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥98%
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AssaySDS-PAGE
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Biological activityDetermined by its ability to induce apoptosis in MCF-7 cells using a concentration range of 20-40 ng/ml.
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Results20-40 ng/ml
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Molecular Weight18.3 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionLyophilized from a concentrated (1 mg/ml) solution in H₂O containing 20 mM sodium Phosphate buffer pH7.5 and 130 mM sodium chloride.
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Reconstitution InstructionsReconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
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Background InformationEndothelial-Monocyte Activating Polypeptide-II (EMAP-II) is a tumor derived cytokine that is an anti-angiogenic factor in tumor Vascular development, and strongly inhibits tumor growth. Recombinant human EMAP-II is an 18.3 kDa protein containing 166 amino acid residues.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolEML1, EML2, EML5, AIMP1
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Short nameEMAP II, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameEMAP II, H. sapiens Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameEMAP like 1
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Synonyms gene
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Synonyms gene name
- echinoderm microtubule associated protein like 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-07-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- EMAP like
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameEMAP like 2
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Synonyms gene name
- echinoderm microtubule associated protein like 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- EMAP like
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameEMAP like 5
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Synonyms gene name
- echinoderm microtubule associated protein like 5
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-17
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Entrez gene record
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Classification
- WD repeat domain containing
- EMAP like
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameaminoacyl tRNA synthetase complex interacting multifunctional protein 1
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Synonyms gene
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Synonyms gene name
- small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-04-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data