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BMPR1A human recombinant

BMPR1A human recombinant is available 2 times from Biovision labs

4881-10 | BMPR1A, human recombinant size: 10 ug | 443.13 USD

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4881-1000 | BMPR1A, human recombinant size: 1 mg | 6,945.56 USD

Catalog number 4881-1000
Supplier Biovision
Price 6,945.56 USD
Size 1 mg
1. Gene info
Identity 1076
Gene BMPR1A
Long gene name bone morphogenetic protein receptor type 1A
Synonyms gene
  • ACVRLK3
Synonyms gene name
  • bone morphogenetic protein receptor, type IA
Synonyms
  • ALK3
  • CD292
GenBank acession
  • BC028383
Locus 10q23.2
Discovery year 1994-12-12
Entrez gene record 657
Pubmed identfication
  • 8397373
  • 9730621
RefSeq identity
  • NM_004329
Classification
  • Type 1 receptor serine/threonine kinases
  • CD molecules
Havana BLAST/BLAT OTTHUMG00000018657
Locus Specific Databases
  • LRG_298
Product images
    #Human#.jpg#0#.jpegBMPR1A, human recombinant
Synonyms BMPR-1A, BMP-R1A, BMPR1A, BMR1A, CD292, CD-292
Alternative_names BMPR-1A, BMP-R1A, BMPR1A, BMR1A, CD292, CD-292, Activin receptor-like kinase 3, Serine/threonine-protein kinase receptor R5, CD_antigen=CD292
Description A transmembrane serine/threonine kinases
Recombinant Yes
Source Insect cells (Baculovirus)
Purity by SDS-PAGE ≥90%
Assay SDS-PAGE
Purity ≥90%
Biological activity Measured by its ability to inhibit recombinant human BMP-2 induced alkaline phosphatase production by C2C12 myogenic cells. The ED₅₀ for this effect is typically 1-3 µg/ml in the presence of 500 ng/ml of recombinant human BMP-2.
Molecular Weight 23.0 kDa
Storage Temp. -20°C
Shipping Blue ice
Shelf Life 12 months
Appearance Lyophilized protein
Physical form description Lyophilized from sterile PBS.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile PBS to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers.
Background Information The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the Activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kDa and type II receptors of about 70-80 kDa. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1A Human Recombinant extracellular domain produced in baculovirus is a monomeric, glycosylated, polypeptide chain fused with 6xHis tag at C-terminus and having a molecular mass of 23 kDa. The BMR1A is purified by proprietary chromatographic techniques.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetBMPR1A
Short name BMPR1A, recombinant
Technique Recombinant
Species Human
Alternative name bone morphogenetic protein receptor, classification IA, H. sapiens recombinant
Alternative technique rec
Alternative to gene target bone morphogenetic protein receptor, type IA, 10q23del and ACVRLK3 and ALK3 and CD292 and SKR5, BMPR1A and IDBG-81081 and ENSG00000107779 and 657, transferase activity, Cell surfaces, Bmpr1a and IDBG-149689 and ENSMUSG00000021796 and 12166, BT.48514 and IDBG-631434 and ENSBTAG00000000231 and 404101
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