anti-TEM7 Antibody

• Catalog number
  4339
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  TEM7 Antibody: Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist; these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.
• Gene names
  TEM7 Antibody: TEM3, TEM7, TEM3, Plexin domain-containing protein 1, Tumor endothelial marker 3
• Antibodie s label
  unlabelled serum
• Purity
  TEM7 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  TEM7 antibody was made against a 16 amino acid synthetic peptide from near the carboxy terminus of human TEM7.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  TEM7 antibody can be used for detection of TEM7 by Western blot at 0.5 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  TEM7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TEM7 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  14017379
• Ncbi nr
  AAG00869
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  57125
• GENE symbol
  PLXDC1
• Antigene name
  plexin domain containing 1
• Source
  Homo sapiens
• Protein nr
  Q8IUK5
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TEM7  
• Gene symbol
  PLXDC1
• Short name
  anti-TEM7 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTEM7 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20945
• Gene
  PLXDC1
• Long gene name
  plexin domain containing 1
• Synonyms
  • TEM3
  • TEM7
• Synonyms name
  • tumor endothelial marker 7 precursor
• GenBank acession
  • AF279144
• Locus
  17q12
• Discovery year
  2003-08-27
• Entrez gene record
  57125
• Pubmed identfication
  • 10947988
  • 11559528
• RefSeq identity
  • NM_020405
• VEGA ID
  OTTHUMG00000133183

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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