Human CellExp™ IL20RB /IL-20R2, human recombinant

  • Catalog number
    7447-10
  • Price
    Please ask
  • Size
    10 ug
  • Synonyms
    IL20RB, IL-20R2, IL-20R-beta, DIRS1, FNDC6
  • Alternative_names
    IL20RB, IL-20R2, IL-20R-beta, DIRS1, FNDC6
  • Description
    A receptor for IL19, IL20 and IL24
  • Recombinant
    Yes
  • Source
    HEK293 cells
  • Purity by SDS PAGE
    ≥90%
  • Assay
    SDS-PAGE
  • Biological activity
    Measured by its binding ability in a functional ELISA. When Recombinant Human IL‑19 protein is present at 0.2 µg/mL, the concentration of rhIL20RB Fc Chimera that produces 50% of the optimal binding response is approximately 5‑50 ng/ml.
  • Results
    Measured by its binding ability in a functional ELISA. When Recombinant Human IL‑19 protein is present at 0.2 µg/mL, the concentration of rhIL20RB Fc Chimera that produces 50% of the optimal binding response is approximately 5‑50 ng/ml.
  • Molecular Weight
    This protein fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 49.1 kDa. The predicted N-terminus is Asp 30. As a result of glycosylation, DTT-reduced Protein migrates as 50 kDa and non-reduced protein migrates as 100 kDa.
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in 50 mM tris, 100 mM glycine, pH 7.0. Normally Mannitol or Trehalose is added as protectants before lyophilization.
  • Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
  • Background Information
    Interleukin-20 receptor subunit beta (IL20RB) is also known as IL-20R2, DIRS1, which belongs to the type II cytokine receptor family. IL20RB / IL-20R2 contains two fibronectin type-III domains. IL20RB / IL-20R2 is widely expressed with highest levels in skin and testis. IL20RB can be fused with IL20RA or IL22RA1 forming heterodimer. The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    IL20RB, IL20RB-AS1, IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17A
  • Short name
    CellExp™ IL20RB /IL-20R2, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ interleukin 20 receptor b /Interleukin-20R2, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    interleukin 20 receptor beta, IL20RB and IDBG-58036 and ENSG00000174564 and 53833, interleukin-20 binding, Plasma membranes, Il20rb and IDBG-193159 and ENSMUSG00000044244 and 213208, IL20RB and IDBG-638656 and ENSBTAG00000008299 and 534581
Gene info
  • Identity
  • Gene
  • Long gene name
    interleukin 20 receptor subunit beta
  • Synonyms gene
  • Synonyms gene name
    • fibronectin type III domain containing 6
    • interleukin 20 receptor beta
    • interleukin 20 receptor beta subunit
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-05-23
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Interleukin receptors
    • Fibronectin type III domain containing
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    IL20RB antisense RNA 1
  • Synonyms gene name
    • IL20RB antisense RNA 1 (non-protein coding)
  • Locus
  • Discovery year
    2011-07-28
  • Classification
    • Antisense RNAs
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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