Tumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, TNF-R1, TNF-R, Tumor Necrosis Factor Receptor Type I, TNFRI, TNFR-I, TNF-RI, TNF-R-I, CD120a, FPF, p55, p55-R, p60, TNF-R55, TNFRp55, TNFR60, Tumor Necrosis Factor alpha Receptor, TNFAR, TN

• Catalog number
  MBS631917
• Price
  Please ask
• Size
  1 mL

• Products_type
  Antibody
• Products_short_name
  [Tumor Necrosis Factor Receptor 1, p55/p60]
• Products_name_syn
  [Anti -Tumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, TNF-R1, TNF-R, Tumor Necrosis Factor Receptor Type I, TNFRI, TNFR-I, TNF-RI, TNF-R-I, CD120a, FPF, p55, p55-R, p60, TNF-R55, TNFRp55, TNFR60, Tumor Necrosis Factor alpha Receptor, TNFAR, TN]
• Other_names
  [tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily member 1A; TNF-R1; TNF-RI; TNFR-I; tumor necrosis factor-alpha receptor; tumor necrosis factor receptor type 1; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily, member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60]
• Other_gene_names
  [TNFRSF1A; TNFRSF1A; FPF; MS5; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55; TNFR1-d2; TNFAR; TNFR1; TNF-R1; TNF-RI; TNFR-I; TBPI]
• Clonality
  Monoclonal
• Clone
  [HM104]
• Reactivity
  Mouse
• Specificity
  Recognizes the extracellular part of the mouse TNF-RI and the soluble receptor. The reactivity of the antibody with soluble TNF-Receptor is inhibited by high concentrations of both mouse and human TNF-alpha.
• Purity
  Purified Purified
• Form
  Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
• Description
  The Tumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, TNF-R1, TNF-R, Tumor Necrosis Factor Receptor I, TNFRI, TNFR-I, TNF-RI, TNF-R-I, CD120a, FPF, p55, p55-R, p60, TNF-R55, TNFRp55, TNFR60, Tumor Necrosis Factor alpha Receptor, TNFAR, TN is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Gene
  Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

• Gene target
  Tumor   Necrosis   Factor   Receptor   p55/p60   TNFR   TNFR1   Tnfr-1   TNF-R1   TNF-R   Tumor   Necrosis   Factor   Receptor   TNFRI   TNFR-I   TNF-RI   TNF-R-I   CD120a   FPF   p55   p55-R   p60   TNF-R55   TNFRp55   TNFR60   Tumor   Necrosis   Factor   alpha   Receptor   TNFAR  
• Gene symbol
  TNFRSF1A, TNF, LTBR, TNFRSF1B, FPR3, FABP6, RRAS, DAD1P1, HNRNPR, CLDN4
• Short name
  Tumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, TNF-R1, TNF-R, Tumor Necrosis Factor Receptor I, TNFRI, TNFR-I, TNF-RI, TNF-R-I, CD120a, FPF, p55, p55-R, p60, TNF-R55, TNFRp55, TNFR60, Tumor Necrosis Factor alpha Receptor, TNFAR, TN
• Host
  Rat
• Isotype
  IgG2a
• Alternative name
  Tumor Necrosis Factor Receptor 1, p55/p60 (TNFR 1, TNFR1, Tnfr-1, tumor necrosis factor-R1, tumor necrosis factor-R, Tumor Necrosis Factor Receptor classification I, TNFRI, TNFR-I, tumor necrosis factor-RI, tumor necrosis factor-R-I, CD120a, FPF, p55, p55-R, p60, tumor necrosis factor-R55, TNFRp55, TNFR60, Tumor Necrosis Factor a Receptor, TNFAR, TN
• Alternative to gene target
  tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
• Tissue
  tumor

Gene info

• Identity
  HGNC:11916
• Gene
  TNFRSF1A
• Long gene name
  TNF receptor superfamily member 1A
• Synonyms gene
  • TNFR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1A
• Synonyms
  • TNF-R
  • TNFAR
  • TNFR60
  • TNF-R-I
  • CD120a
  • TNF-R55
• GenBank acession
  • M75866
• Locus
  12p13.31
• Discovery year
  1991-01-15
• Entrez gene record
  7132
• Pubmed identfication
  • 1655358
  • 2158863
• RefSeq identity
  • NM_001065
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000168267
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_193

Gene info

• Identity
  HGNC:11892
• Gene
  TNF
• Long gene name
  tumor necrosis factor
• Synonyms gene
  • TNFA
• Synonyms gene name
  • tumor necrosis factor (TNF superfamily, member 2)
• Synonyms
  • TNFSF2
  • DIF
  • TNF-alpha
• Synonyms name
  • TNF superfamily, member 2
• GenBank acession
  • X02910
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  7124
• Pubmed identfication
  • 2413547
  • 6392892
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000031194

Gene info

• Identity
  HGNC:6718
• Gene
  LTBR
• Long gene name
  lymphotoxin beta receptor
• Synonyms gene
  • D12S370
• Synonyms
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNF-R-III
  • TNFRSF3
• Synonyms name
  • TNFR superfamily, member 3
• GenBank acession
  • L04270
• Locus
  12p13.31
• Discovery year
  1996-03-12
• Entrez gene record
  4055
• Pubmed identfication
  • 8171323
  • 8486360
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000168356

Gene info

• Identity
  HGNC:11917
• Gene
  TNFRSF1B
• Long gene name
  TNF receptor superfamily member 1B
• Synonyms gene
  • TNFR2
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1B
• Synonyms
  • TNFBR
  • TNFR80
  • TNF-R75
  • TNF-R-II
  • p75
  • CD120b
• GenBank acession
  • M32315
• Locus
  1p36.22
• Discovery year
  1991-01-15
• Entrez gene record
  7133
• Pubmed identfication
  • 2158863
  • 8702885
• RefSeq identity
  • NM_001066
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000001829

Gene info

• Identity
  HGNC:3828
• Gene
  FPR3
• Long gene name
  formyl peptide receptor 3
• Synonyms gene
  • FPRL2
• Synonyms gene name
  • formyl peptide receptor-like 2
• Synonyms
  • FPRH1
  • FMLPY
  • RMLP-R-I
• Locus
  19q13.41
• Discovery year
  1991-12-04
• Entrez gene record
  2359
• Pubmed identfication
  • 1612600
  • 8198572
• RefSeq identity
  • NM_002030
• Classification
  • Formyl peptide receptors
• VEGA ID
  OTTHUMG00000183502

Gene info

• Identity
  HGNC:3561
• Gene
  FABP6
• Long gene name
  fatty acid binding protein 6
• Synonyms gene name
  • fatty acid binding protein 6, ileal
• Synonyms
  • I-15P
  • ILLBP
  • I-BAP
  • ILBP3
  • I-BABP
  • ILBP
  • I-BALB
• Synonyms name
  • illeal lipid-binding protein
  • ileal bile acid binding protein
  • gastrotropin
• GenBank acession
  • U19869
• Locus
  5q33.3
• Discovery year
  1997-09-12
• Entrez gene record
  2172
• Pubmed identfication
  • 7894165
  • 7619861
• RefSeq identity
  • NM_001040442
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000130329

Gene info

• Identity
  HGNC:10447
• Gene
  RRAS
• Long gene name
  RAS related
• Synonyms gene name
  • related RAS viral (r-ras) oncogene homolog
• Synonyms
  • R-Ras
• Synonyms name
  • Oncogene RRAS
• Locus
  19q13.33
• Discovery year
  2001-06-22
• Entrez gene record
  6237
• Pubmed identfication
  • 3098437
• RefSeq identity
  • NM_006270
• Classification
  • RAS type GTPase family
• VEGA ID
  OTTHUMG00000183247

Gene info

• Identity
  HGNC:18295
• Gene
  DAD1P1
• Long gene name
  defender against cell death 1 pseudogene 1
• Synonyms gene
  • DAD1L
• Synonyms gene name
  • defender against cell death 1-like
• Synonyms
  • DAD-R
• Locus
  12p12.1
• Discovery year
  2007-07-26
• Entrez gene record
  56286
• Pubmed identfication
  • 10812081
  • 11912161
• RefSeq identity
  • NR_024064

Gene info

• Identity
  HGNC:5047
• Gene
  HNRNPR
• Long gene name
  heterogeneous nuclear ribonucleoprotein R
• Synonyms gene
  • HNRPR
• Synonyms
  • hnRNP-R
• GenBank acession
  • AF000364
• Locus
  1p36.12
• Discovery year
  1999-06-11
• Entrez gene record
  10236
• Pubmed identfication
  • 9421497
• RefSeq identity
  • NM_005826
• Classification
  • Heterogeneous nuclear ribonucleoproteins
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000003224

Gene info

• Identity
  HGNC:2046
• Gene
  CLDN4
• Long gene name
  claudin 4
• Synonyms gene
  • CPETR
  • CPETR1
• Synonyms
  • CPE-R
  • WBSCR8
  • hCPE-R
• Synonyms name
  • Clostridium perfringens enterotoxin receptor 1
  • Williams-Beuren syndrome chromosomal region 8 protein
• GenBank acession
  • AB000712
• Locus
  7q11.23
• Discovery year
  1998-04-22
• Entrez gene record
  1364
• Pubmed identfication
  • 9334247
  • 9892664
• RefSeq identity
  • NM_001305
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000023425

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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