-
Target antigen
Kallikrein 4
-
Clonality
Polyclonal antibody
-
Clone
Polyclonal antibody
-
Raised in
rabbit
-
Type of the antibody
IgG polyclonal antibody
-
Product form
freeze-dried
-
Reacts with species
Human. No cross reactivity with other proteins.
-
Analyses
WB
-
Immunogen
E.coli-derived human Kallikrein 4 recombinant protein (Position: I31-S254).
-
Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
-
Purification
Immunogen affinity purified.
-
Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
-
Storage condtions
Keep the Kallikrein 4 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
-
Tips
The Kallikrein 4 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
-
Background
Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer. It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.
-
Related articles
1. Klokk, T. I., Kilander, A., Xi, Z., Waehre, H., Risberg, B., Danielson, H. E., Saatcioglu, F. Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer. Cancer Res. 67: 5221-5230, 2007. 2. Nelson PS, Gan L, Ferguson C, Moss P, Gelinas R, Hood L, Wang K (March 1999). 3. Simmer JP, Fukae M, Tanabe T, Yamakoshi Y, Uchida T, Xue J, Margolis HC, Shimizu M, DeHart BC, Hu CC, Bartlett JD (June 2000).
-
Gene Name
KLK4
-
Protein Name
Kallikrein-4
-
Gene Full Name
kallikrein-related peptidase 4
-
Synonyms
7S nerve growth factor alpha chain antibody|AI2A1 antibody|Alpha-NGF antibody|Androgen-regulated message 1 antibody|ARM1 antibody|EC 3.4.21.- antibody|EMSP 1 antibody|EMSP antibody|EMSP1 antibody|Enamel Matrix Serine Protease 1 antibody|Enamel matrix serine proteinase 1 antibody|HK4 antibody|Kallikrein 1-related peptidase-like b4 antibody|Kallikrein 4 (prostase, enamel matrix, prostate) antibody|Kallikrein 4 antibody|Kallikrein antibody|Kallikrein L1 antibody|Kallikrein like protein 1 antibody|Kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) antibody|Kallikrein-4 antibody|Kallikrein-like protein 1 antibody|Kallikrein-related peptidase 4 antibody|KLK 4 antibody|KLK L1 antibody|KLK-L1 antibody|KLK4 antibody|KLK4_HUMAN antibody|MGC116827 antibody|MGC116828 antibody|Prostase antibody|Protease Serine 17 antibody|PRSS 17 antibody|PRSS17 antibody|PSTS antibody|Serine protease 17 antibody
-
Uniprot ID
Q9Y5K2
-
Entrez GeneID
9622
-
Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps