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NSC 23766 for cell activation

NSC 23766 for cell activation is available 0 time from Biovision labs

Description A cell-permeable, reversible, and selective Rac1 inhibitor; inhibiting Rac1 activation by the Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam 1 (IC₅₀ = 50 μM) without affecting the closely related GTPases, Cdc42, and RhoA activation. NSC 23766 has been used to investigate the role of Rac1 in such diverse cellular functions as stem cell mobilization, epithelial cell migration, angiogenesis, leukemia cell migration and growth, etc.
Peptide sequence N/A
CAS number 733767-34-5
Molecular weight 530.97
Category Biochemicals
Other name N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
Molecular formula C₂₄H₃₅N₇.3HCl
Physical appearance White solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Reconstitute instructions Water (100 mM)
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from light and moisture
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetNSC 23766 for activation
Short name NSC 23766 for activation
Technique activation
Alternative name NSC 23766 to measure cellular activation
Tissue cell
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