Deprenyl, Apoptosis Inhibitor
-
Catalog number
SIH-209-100MG
-
Price
Please ask
-
Size
100 mg
-
-
Stock availabilitIn Stock
In Stock
-
CAS number
14611-52-0
-
Description
Apoptosis Inhibitor
-
Molecular weight
223,74 g/mol
-
Primary research fields
Cancer, Apoptosis
-
Other name
N-Methyl-N-[(2R)-1-phenyl-2-propanyl]-2-propyn-1-amine, Selegiline
-
Product category
Small Molecules
-
Product type
Inhibitor
-
Chemical formula
C13H17N·HCl
-
Origin
Synthetic
-
Purity pourcentage
>99%
-
Soluble in
Soluble to 100 mM in water, and to 100 mM in ethanol
-
Physical appearance
White Solid
-
Storage recommendations
-20ºC
-
Shipping recommendations
Shipped Ambient
-
Safety information
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62- Possible risk of impaired fertility
-
PubChem number
26757
-
Scientific context
Deprenyl or Selegiline is a drug used for the treatment of early stage Parkinson’s (1), depression and senile dementia (2). It is a selective irreversable inhibitor of monoamine oxidase B (MAO-b).
-
Bibliography
1. Lachenmayer L., and Laux G. (2004) Curr Med Chem. 11(15): 2033-2043. 2. FDA US Food and Drug Administration. Press Announcements Feb 28, 2006. www.fda.gov/newsevents/newsroom/pressannouncements/2006/ucm108607.htm
-
Release date
8-Apr-2011
-
PubMed number
Refer to PubMed
-
Tested applications
To be tested
-
Tested reactivity
To be tested
-
-
Representative figure legend
Chemical structure of Deprenyl (SIH-209), a glyceraldehyde-3-phosphate dehydrogenase inhibitor. CAS #: 14611-52-0. Molecular Formula: C13H17N · HCl . Molecular Weight: 223.74 g/mol. Chemical structure of Deprenyl, a glyceraldehyde-3-phosphate dehydrogenase inhibitor (SIH-209). CAS # 14611-52-0. Molecular Formula: C13H17N · HCl .
-
Warning information
Non-hazardous
-
Country of production
Canada
-
Total weight kg
0.25
-
Net weight g
0.1
-
-
Additional description
This 1 is suited for programmed cell-death studies. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
-
Gene target
-
Short name
Deprenyl, Apoptosis Inhibitor
-
Technique
apoptosis, apoptosis pathway
-
Alternative name
Deprenyl, programmed cellular destruction suppressor
-
Alternative technique
celldeath
-
Similar products