Filters
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing

API5 Antibody ALEXA FLUOR

API5 Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-1252R-A350 | API5 Antibody, ALEXA FLUOR 350 size: 100ul | 380.23 USD

Loading

bs-1252R-A488 | API5 Antibody, ALEXA FLUOR 488 size: 100ul | 380.23 USD

Loading

bs-1252R-A555 | API5 Antibody, ALEXA FLUOR 555 size: 100ul | 380.23 USD

Loading

bs-1252R-A594 | API5 Antibody, ALEXA FLUOR 594 size: 100ul | 380.23 USD

Loading

bs-1252R-A647 | API5 Antibody, ALEXA FLUOR 647 size: 100ul | 380.23 USD

Long name API5 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
Also known as Anti-API5 PAb ALEXA FLUOR 647
Conjugated with ALEXA FLUOR® 647
Excitation emission 650nm/665nm
Properties For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the API5 Antibody, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor,ALEXA FLUOR 647
French translation anticorps
Label ALEXA FLUOR 647
Alternative name apoptosis inhibitor 5 (Antibody to), ALEXA FLUOR 647
1. Gene info
Identity594
GeneAPI5
Long gene name apoptosis inhibitor 5
GenBank acession
Locus11p12
Discovery year 1998-10-06
Entrez gene record8539
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000166395
2. Gene info
Identity595
GeneAPI5P1
Long gene name apoptosis inhibitor 5 pseudogene 1
Synonyms gene
Synonyms gene name
  • API5-like 1
  • API5 pseudogene 1
LocusXq23
Discovery year 1999-07-14
Entrez gene record642812
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000022242
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedrs17684886 (ZNRF1) and rs599019 (COLEC12) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1) and rs899036 (API5) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes
The authors report here that AAC-11, a survival protein whose expression prevents apoptosis that occurs on deprivation of growth factors, physiologically binds to Acinus and prevents Acinus-mediated DNA fragmentation.
define a true in vivo target of miR-224 and reaffirm the important role of miRNAs in the dysregulation of cellular processes that may ultimately lead to tumorigenesis
The prognostic significance of the genes casein kinase 2 alpha subunit (CSNK2A1), anti-apoptosis clone-11 (AAC-11), and tumor metastasis suppressor NME1 in completely resected non-small cell lung cancer (NSCLC) patients, was analysed.
Api5, even if not physically interacting with E2F1, contributes positively to E2F1 transcriptional activity by increasing E2F1 binding to its target promoters.
API5 acts as an immune escape gene in tumors by rendering them resistant to apoptosis triggered by tumor antigen-specific T cells.
Low miR-224 and high API5 expression correlated with worse survival of glioblastoma patients.
API5 overexpression promoted cell proliferation and colony formation in CaSki cancer cells, whereas API5 knockdown inhibited the both properties in HeLa cells; API5 expression is associated with pERK1/2 in a subset of cervical cancer patients and its expression predicts poor overall survival.
Negative regulation of API-5 expression by miR-1 was demonstrated to promote apoptosis of HepG2 cells.
miR-143 and miR-145 and the predicted target proteins API5, ERK5, K-RAS, and IRS-1 display regional differences in expression in the colon
Product images
    #bs#.jpgLane A: Mouse Heart lysate Lane B: Mouse Pancreas lysates probed with Rabbit Anti-API5 Polyclonal Antibody, Unconjugated (bs-1252R) at 1:300 overnight at 4˚C. Followed by HRP conjugated Goat-Anti-Rabbit IgG(bse-0295G-HRP)  at 1:5000 for 90 min at 37˚C. \\n#.png
Product files
Modification Unmodified
Clonality Polyclonal
Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human API5
Swiss Prot Q9BZZ5
Specificity This is a highly specific antibody against API5.
Immunogen range 345-395/524
Subcellular location Cytoplasm, Nucleus
Tested applications IF(IHC-P)
Clone Polyclonal antibody
Modification Site None
Synonyms AAC11; AAC-11; Apoptosis inhibitor 5; API-5; Antiapoptosis clone 11 protein; Cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; FIF; Protein XAGL; API5; MIG8
Purification Purified by Protein A.
Crossreactivity Human, Mouse, Rat
Gene ID Number 8539
Recommended dilutions IF(IHC-P)(1:50-200)
Background of the antigen Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Concentration 1ug per 1ul
Target Antigen API5
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Gene targetAPI5
Short name API5 Antibody,
Technique Antibody
Alternative technique antibodies
Alternative to gene target apoptosis inhibitor 5, AAC-11 and AAC11, API5 and IDBG-40293 and ENSG00000166181 and 8539, poly(A) RNA binding, nuclei, Api5 and IDBG-193023 and ENSMUSG00000027193 and 11800, API5 and IDBG-636799 and ENSBTAG00000014474 and 538968
Similar products
CCL26 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
IL-31 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
C3orf24 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
Histone H2A Ubiquityl Lys119 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
NFKBIA Tyr42 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 400.12 USD
ABHD14B Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
IFI30 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
GNRHR2 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
Complement C3 beta chain Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
CLN8 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
PI3KCA Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
LAR PTPRF Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
GABRP GABA A receptor pi Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
RAR Beta Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
MYPT1 Ser507 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 400.12 USD
NSUN6 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
RNF142 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
GIT2 Antibody ALEXA FLUOR Suppplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR
Price: 380.23 USD
Ask
Ajax processing
Close
API5 Antibody ALEXA FLUOR - Gentaur.com
Filters
+32-(0)1-658-90-45 lieven@gentaur.com
Contact us
Ajax processing
Close
Chat with gentaur.com employee