MRGPRX1/3/4 Antibody, ALEXA FLUOR 594
-
Catalog number
bs-6606R-A594
-
Price
Please ask
-
Size
100ul
-
-
Long name
MRGPRX1/3/4 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
-
Also known as
Anti-MRGPRX1/3/4 PAb ALEXA FLUOR 594
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 594
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
MRGPRX1/3/4
-
Specificity
This is a highly specific antibody against MRGPRX1/3/4.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Immunogen range
1-35/322
-
Subcellular location
Extracellular
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MRGX1
-
Gene ID Number
259249, 117195, 117196
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways. G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
590nm/617nm
-
Synonyms
MRGPRC; G protein coupled receptor MRGX1; G protein coupled receptor SNSR3; GPCR; Mas related G protein coupled receptor member X1; MAS related gene MRGX1; MAS related GPR member X1; MRGPRX1; MRGX1; Sensory neuron specic G protein coupled receptor 3/4; Seven transmembrane helix receptor; SNSR3; SNSR4; MRGX1_HUMAN; MRGPRX3; MRGX3; MRGPRX4; MRGX4; SNSR5; SNSR6; SNSR1; SNSR2.
-
Properties
For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor, ALEXA FLUOR® 594
-
Conjugated
Alexa conjugate 1
-
French translation
anticorps
-
Gene target
-
Gene symbol
MRGPRX1
-
Short name
Anti-MRGPRX1/3/4
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 594
-
Alternative name
MRGPRX1/3/4 Polyclonal Antibody, ALEXA FLUOR 594
-
Alternative technique
antibodies
-
Alternative to gene target
MAS-related GPR, member X1, MRGPRX1 and IDBG-35377 and ENSG00000170255 and 259249, G-protein coupled receptor activity, Plasma membranes
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products