ABIN-1 (A-20 Binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation, HIV-1 Nef-interacting Protein, KIAA0113, Nef-associated Factor 1, Naf1, Nip40-1, TNFAIP3 Interacting Protein 1, TNIP1, Virion-associated Nuclear Shuttling Protein, VAN, hVAN)

• Catalog number
  MBS619272
• Price
  Please ask
• Size
  0,1 mL

• Other size
  please contact us to order other different size
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• Gene
  The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome(AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. recombinant HIV 1 and 2 gag gene proteins p24, p17, p55 immunodominant epitopes and envelope glycoproteins, gp120 are used for production of diagnostic detection antibodies.

• Gene target
  ABIN-1   A-20   Binding   Inhibitor   Factor-kappaB   NF-kB   Activation   HIV-1   Nef-interacting   Protein   KIAA0113   Nef-associated   Factor   Naf1   Nip40-1   TNFAIP3   Interacting   Protein   TNIP1   Virion-associated   Shuttling   Protein   VAN   hVAN  
• Gene symbol
  TNIP1, TNFAIP3, NFYB, NFE4, NFE2, GATA1, IGHVII-20-1, NEFH, NFKB1, YY1
• Short name
  ABIN-1 (A-20 Binding Inhibitor of Factor-kappaB (NF-kB) Activation, HIV-1 Nef-interacting Protein, KIAA0113, Nef-associated Factor 1, Naf1, Nip40-1, TNFAIP3 Interacting Protein 1, TNIP1, Virion-associated Shuttling Protein, VAN, hVAN)
• Technique
  activation
• Alternative name
  ABIN-1 (A-20 Binding suppressor on Nuclear Factor-kappaB (NF-kB) Activation, human immunodeficiency virus-1 Nef-interacting Protein, KIAA0113, Nef-associated Factor 1, Naf1, Nip40-1, tumor necrosis factor, a-induced protein 3 Interacting Protein 1, TNFAIP3 interacting protein 1, Virion-associated Nuclear Shuttling Protein, VAN, hVAN)
• Alternative to gene target
  TNFAIP3 interacting protein 1, ABIN-1 and NAF1 and nip40-1 and VAN, TNIP1 and IDBG-54098 and ENSG00000145901 and 10318, mitogen-activated protein kinase binding, nuclei, Tnip1 and IDBG-174207 and ENSMUSG00000020400 and 57783, TNIP1 and IDBG-646318 and ENSBTAG00000012671 and 526103
• Virus
  hiv

Gene info

• Identity
  HGNC:16903
• Gene
  TNIP1
• Long gene name
  TNFAIP3 interacting protein 1
• Synonyms
  • NAF1
  • KIAA0113
  • ABIN-1
  • VAN
• Synonyms name
  • virion-associated nuclear-shuttling protein
  • Nef-associated factor 1 SNP
• GenBank acession
  • AJ011895
• Locus
  5q33.1
• Discovery year
  2002-10-03
• Entrez gene record
  10318
• Pubmed identfication
  • 9923610
  • 11090181
• RefSeq identity
  • NM_006058
• VEGA ID
  OTTHUMG00000163722

Gene info

• Identity
  HGNC:11896
• Gene
  TNFAIP3
• Long gene name
  TNF alpha induced protein 3
• Synonyms gene name
  • tumor necrosis factor, alpha-induced protein 3
• Synonyms
  • A20
  • OTUD7C
• GenBank acession
  • M59465
• Locus
  6q23.3
• Discovery year
  1992-10-20
• Entrez gene record
  7128
• Pubmed identfication
  • 2118515
• Classification
  • OTU domain containing
• VEGA ID
  OTTHUMG00000015664

Gene info

• Identity
  HGNC:7805
• Gene
  NFYB
• Long gene name
  nuclear transcription factor Y subunit beta
• Synonyms gene name
  • nuclear transcription factor Y, beta
• Synonyms
  • CBF-A
  • HAP3
  • NF-YB
• Locus
  12q23.3
• Discovery year
  1991-11-08
• Entrez gene record
  4801
• Pubmed identfication
  • 1774067
  • 9612081
• VEGA ID
  OTTHUMG00000170176

Gene info

• Identity
  HGNC:29902
• Gene
  NFE4
• Long gene name
  nuclear factor, erythroid 4
• Synonyms
  • NF-E4
• Locus
  7q22.1
• Discovery year
  2013-08-23
• Entrez gene record
  58160
• Pubmed identfication
  • 11003662
• RefSeq identity
  • NR_166510
• VEGA ID
  OTTHUMG00000157208

Gene info

• Identity
  HGNC:7780
• Gene
  NFE2
• Long gene name
  nuclear factor, erythroid 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
• Synonyms
  • NF-E2
• GenBank acession
  • BC005044
• Locus
  12q13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4778
• Pubmed identfication
  • 8355703
• RefSeq identity
  • NM_006163
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000169761

Gene info

• Identity
  HGNC:4170
• Gene
  GATA1
• Long gene name
  GATA binding protein 1
• Synonyms gene
  • GF1
• Synonyms gene name
  • GATA-binding protein 1 (globin transcription factor 1)
  • globin transcription factor 1
• Synonyms
  • ERYF1
  • NFE1
  • GATA-1
  • NF-E1
• Synonyms name
  • nuclear factor, erythroid 1
• GenBank acession
  • X17254
• Locus
  Xp11.23
• Discovery year
  1990-09-10
• Entrez gene record
  2623
• Pubmed identfication
  • 1999341
• RefSeq identity
  • NM_002049
• Classification
  • GATA zinc finger domain containing
• VEGA ID
  OTTHUMG00000021504
• Locus Specific Databases
  • LRG_559

Gene info

• Identity
  HGNC:5672
• Gene
  IGHVII-20-1
• Long gene name
  immunoglobulin heavy variable (II)-20-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-20-1
  • immunoglobulin heavy variable (II)-20-1 pseudogene
• Synonyms
  • IGHV(II)-20-1
• GenBank acession
  • AB019440
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28375
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

Gene info

• Identity
  HGNC:12856
• Gene
  YY1
• Long gene name
  YY1 transcription factor
• Synonyms
  • NF-E1
  • DELTA
  • UCRBP
  • YIN-YANG-1
  • INO80S
• Synonyms name
  • INO80 complex subunit S
  • Yin and Yang 1 protein
• GenBank acession
  • BC020324
• Locus
  14q32.2
• Discovery year
  1993-09-17
• Entrez gene record
  7528
• Pubmed identfication
  • 1655281
  • 7912122
• RefSeq identity
  • NM_003403
• Classification
  • INO80 complex
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000150479

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