SREBP1 Antibody

• Catalog number
  3961-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  SREBP1
• Target Alternative Name
  Adipocyte determination- and differentiation-dependent factor 1, ADD1, Sterol regulatory element-binding transcription factor 1
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 318 of rat SREBP1
• Accession
  P56720.
• Gene Id
  78968
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-SREBP1polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Jurkat (Induced and Uninduced), Rat Kidney, 3T3 cell lysates
• Application And Usages
  The antibody can be used for Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 3961BP-50) is available separately.
• Description
  SREBP (Sterol Regulatory Element Binding Protein) 1 and 2 are transcription factors th at regulates cholesterol homeostasis. SREBP proteins are attached to the endoplasmic reticulum and nuclear envelope. SREBP proteins undergo proteolytic cleavage in response to conditions of low cellular sterol. Upon activation of SREBP 1, a soluble NH2 cleavage fragment translocate to the nucleus and activates transcription of enzymes and other proteins required for cholesterol synthesis.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SREBP1  
• Gene symbol
  SREBF1
• Short name
  SREBP1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  SREBP1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11289
• Gene
  SREBF1
• Long gene name
  sterol regulatory element binding transcription factor 1
• Synonyms
  • SREBP1
  • bHLHd1
  • SREBP-1c
  • SREBP1a
• GenBank acession
  • BC057388
• Locus
  17p11.2
• Discovery year
  1994-11-23
• Entrez gene record
  6720
• Pubmed identfication
  • 8402897
  • 7759101
• RefSeq identity
  • NM_004176
• Classification
  • Basic helix-loop-helix proteins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000059313

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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