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Tyrphostin AG 490

Tyrphostin AG 490 is available 1 time from Biovision labs

1570-5 | Tyrphostin AG 490 size: 5 mg | 175.94 USD

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Alternative_name 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide; 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide, AG 490
Description Selectively inhibits EGF receptor auto-phosphorylation (IC₅₀ = 100 µM) and selectively inhibits DNA synthesis and cell growth; induces apoptosis. A JAK2 inhibitor. Blocks growth of leukemia cells in vivo and in vitro.
CAS Number 133550-30-8
Structure Available? Yes
Salt Form No
Molecular Formula C₁₇H₁₄N₂O₃
Molecular Weight 294.31
Cell-Permeable? Yes
Purity ≥99%
Solubilities DMSO (100 mM) and ETOH (20 mM)
Handling Protect from light and air
Tag Line An EGFR inhibitor
Storage Condition -20°C
Shipping Condition gel pack
Shelf Life 24months
MDL Number MFCD00236452
PubChem CID 5328779
SMILES C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
InChi InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
InChi Key TUCIOBMMDDOEMM-RIYZIHGNSA-N
MSDS Available Yes
Gene targetTyrphostin 490
Short name Tyrphostin AG 490
Alternative name Tyrphostin AG 490
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