IL-17F, human recombinant

  • Catalog number
    4176F-25
  • Price
    Please ask
  • Size
    25 ug
  • Synonyms
    none
  • Alternative_names
    IL-17, Interleukin 17, Cytokine ML-1, Interleukin-24
  • Description
    A proinflammatory cytokine produced by activated T cells
  • Recombinant
    Yes
  • Source
    E. coli
  • Purity by SDS PAGE
    ≥98%
  • Assay
    SDS-PAGE
  • Purity
    ≥98%
  • Biological activity
    The ED₅₀ as determined by the dose-dependent induction of IL-6 in NIH-3T3 cells was found to be approximately 10 ng/ml, corresponding to a specific activity of 1.0 x 10⁵ IU/mg
  • Results
    10 ng/ ml
  • Molecular Weight
    30.1 kDa
  • Storage Temp
    -20°C
  • Shipping
    Blue ice
  • Shelf Life
    12 months
  • Appearance
    Lyophilized protein
  • Physical form description
    Lyophilized from a concentrated solution (1 mg/ml) containing 20 mM phosphate buffer (ph 7.4).
  • Reconstitution Instructions
    The lyophilized IL-17F can be reconstituted in H₂O to a concentration of 0.1-1.0 µg/µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.
  • Background Information
    IL-17Fis a member of the IL-17 family of structurally-related cytokines. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F stimulates proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant human IL-17F is a 30.1 kDa consisting of two 134 amino acid polypeptide chains.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    IL-17F  
  • Gene symbol
    IL17F, IL36G, IL25, IL22, IL18, IL37, IL6R, IL17C, IL17D, IL17A
  • Short name
    IL-17F, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Interleukin-17F, H. sapiens Rec.
  • Alternative technique
    rec
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
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Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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