GCP-2 (CXCL6), human recombinant

• Catalog number
  7153-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  CXCL6
• Alternative_names
  CXCL6
• Description
  A CXC chemokine that can signal through the CXCR1 and CXCR2 receptors
• Recombinant
  Yes
• Source
  E. coli.
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 0.1 ng/ug of protein (
• Activity Specifications test method
  Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.
• Biological activity
  Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.
• Molecular Weight
  7.9 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized powder
• Physical form description
  Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM acetic acid.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
• Background Information
  GCP-2 is a connective tissue derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. GCP-2 selectively attracts neutrophils and has also been shown to exert angiogenic activity. Human GCP-2 is cross-react on murine cells. Recombinant human GCP-2 is a 7.9 kDa protein containing 72 amino acid residues.
• Amino acid sequence
  VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  GCP-2   CXCL6  
• Gene symbol
  CXCL6, TUBGCP2, NEDD1, GOLGA4, GOLGB1, OPN1MW, FOLH1, MIR1289-2, MIR521-2, MIR509-2
• Short name
  GCP-2 (CXCL6), recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  GCP-2 (chemokine (C-X-C motif) ligand 6), H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  chemokine (C-X-C motif) ligand 6, CKA-3 and GCP-2 and GCP2 and SCYB6, CXCL6 and IDBG-24017 and ENSG00000124875 and 6372, heparin binding, Extracellular

Gene info

• Identity
  HGNC:10643
• Gene
  CXCL6
• Long gene name
  C-X-C motif chemokine ligand 6
• Synonyms gene
  • SCYB6
• Synonyms gene name
  • small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2)
  • chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
  • chemokine (C-X-C motif) ligand 6
• Synonyms
  • GCP-2
  • CKA-3
• Synonyms name
  • granulocyte chemotactic protein 2
• GenBank acession
  • U83303
• Locus
  4q13.3
• Discovery year
  1997-10-09
• Entrez gene record
  6372
• Pubmed identfication
  • 9465307
• RefSeq identity
  • NM_002993
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000130010

Gene info

• Identity
  HGNC:18599
• Gene
  TUBGCP2
• Long gene name
  tubulin gamma complex associated protein 2
• Synonyms gene name
  • tubulin, gamma complex associated protein 2
• Synonyms
  • GCP2
  • Spc97p
  • SPBC97
• GenBank acession
  • AF042379
• Locus
  10q26.3
• Discovery year
  2002-08-14
• Entrez gene record
  10844
• Pubmed identfication
  • 9566967
• VEGA ID
  OTTHUMG00000019319

Gene info

• Identity
  HGNC:7723
• Gene
  NEDD1
• Long gene name
  NEDD1 gamma-tubulin ring complex targeting factor
• Synonyms gene name
  • neural precursor cell expressed, developmentally down-regulated 1
• Synonyms
  • GCP-WD
  • TUBGCP7
• Synonyms name
  • tubulin gamma complex associated protein 7
• Locus
  12q23.1
• Discovery year
  1994-01-21
• Entrez gene record
  121441
• Classification
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000170604

Gene info

• Identity
  HGNC:4427
• Gene
  GOLGA4
• Long gene name
  golgin A4
• Synonyms gene name
  • golgi autoantigen, golgin subfamily a, 4
• Synonyms
  • GOLG
  • GCP2
  • p230
  • golgin-240
• Synonyms name
  • golgin 245
• GenBank acession
  • U31906
• Locus
  3p22.2
• Discovery year
  1997-11-05
• Entrez gene record
  2803
• Pubmed identfication
  • 8626529
• RefSeq identity
  • NM_002078
• Classification
  • Golgins
• VEGA ID
  OTTHUMG00000130799

Gene info

• Identity
  HGNC:4429
• Gene
  GOLGB1
• Long gene name
  golgin B1
• Synonyms gene name
  • golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1
  • golgin B1, golgi integral membrane protein
• Synonyms
  • GCP
  • GCP372
  • giantin
  • GOLIM1
• Synonyms name
  • macrogolgin
  • golgi integral membrane protein 1
• GenBank acession
  • X75304
• Locus
  3q13.33
• Discovery year
  1997-11-05
• Entrez gene record
  2804
• Pubmed identfication
  • 7691276
  • 15004235
• RefSeq identity
  • NM_004487
• Classification
  • Golgins
• VEGA ID
  OTTHUMG00000159411

Gene info

• Identity
  HGNC:4206
• Gene
  OPN1MW
• Long gene name
  opsin 1, medium wave sensitive
• Synonyms gene
  • GCP
  • CBBM
  • CBD
• Synonyms gene name
  • color blindness, deutan
  • green cone photoreceptor pigment
  • opsin 1 (cone pigments), medium-wave-sensitive
• Synonyms
  • OPN1MW1
  • COD5
• Synonyms name
  • cone dystrophy 5 (X-linked)
• GenBank acession
  • K03494
• Locus
  Xq28
• Discovery year
  2001-06-22
• Entrez gene record
  2652
• RefSeq identity
  • NM_000513
• Classification
  • Opsin receptors
• VEGA ID
  OTTHUMG00000022652
• Locus Specific Databases
  • Mutations of the Photopigments - Red (RCP), Green (GCP), and Blue Cone Pigment (BCP)

Gene info

• Identity
  HGNC:3788
• Gene
  FOLH1
• Long gene name
  folate hydrolase 1
• Synonyms gene
  • FOLH
• Synonyms gene name
  • folate hydrolase (prostate-specific membrane antigen) 1
• Synonyms
  • PSM
  • PSMA
  • NAALAD1
  • NAALAdase
  • GCP2
  • GCPII
• Synonyms name
  • glutamate carboxylase II
  • glutamate carboxypeptidase 2
• GenBank acession
  • M99487
• Locus
  11p11.12
• Discovery year
  1996-12-16
• Entrez gene record
  2346
• Pubmed identfication
  • 9838072
• RefSeq identity
  • NM_004476
• Classification
  • M28 metallopeptidases
• VEGA ID
  OTTHUMG00000166625

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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