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2 Deoxy D Glucose

2 Deoxy D Glucose is available 4 times from Biovision labs

B1048-100 | 2-Deoxy-D-Glucose size: 2X100 mg | 315.93 USD

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B1048-500 | 2-Deoxy-D-Glucose size: 500 mg | 407.06 USD

Catalog number B1048-500
Supplier Biovision
Price 407.06 USD
Size 500 mg
Gene target2-Deoxy-D-Glucose
Short name 2-Deoxy-D-Glucose
Alternative name 2-Deoxy-D-Glucose
1. Gene info
Identity 13935
Gene LY6G6D
Long gene name lymphocyte antigen 6 family member G6D
Synonyms gene
  • C6orf23
Synonyms gene name
  • chromosome 6 open reading frame 23
  • lymphocyte antigen 6 complex, locus G6D
Synonyms
  • MEGT1
  • Ly6-D
  • G6D
  • LY6-D
  • NG25
Locus 6p21.33
Discovery year 2002-04-05
Entrez gene record 58530
Pubmed identfication
  • 12079290
Classification
  • LY6/PLAUR domain containing
Havana BLAST/BLAT OTTHUMG00000137370
Product images
    #0#.jpeg2-Deoxy-D-Glucose

B1048-500 | 2-Deoxy-D-Glucose for cell activation size: 500 mg | 304.99 USD

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B1048-100 | 2-Deoxy-D-Glucose for cell activation size: 100 mg | 133.66 USD

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Alternate Name/Synonyms 2-Deoxy-D-arabinohexose, 2-Deoxyglucose
Appearance White to off-white solid
Formulation N/A
CAS Number 154-17-6
Peptide sequence N/A
Molecular Formula C₆H₁₂O₅
Molecular Weight 164.16
Purity ≥98% GC
Solubility/Reconstitution Instructions H2O (>15 mg/ml) or DMSO (>15 mg/ml)
Handling Protect from air and moisture
Tagline A competitive inhibitor of glucose metabolism.
Storage Temp. +4°C
Shipping Conditions gel pack
Shelf Life 36 months
MDL Number MFCD00151328
PubChem CID 439268
Category Biochemicals
Description 2-Deoxy-D-Glucose is a glucose analog that has long been known to act as a competitive inhibitor of glucose metabolism. Upon transport into the cells, 2-DG is phosphorylated by hexokinase to 2-DG-P. However, unlike G-6-P, 2-DG-P cannot be further metabolized by phosphohexose isomerase, which converts G-6-P to fructose-6-phosphate . 2-Deoxyglucose-P is trapped and accumulated in the cells, leading to inhibition of glycolysis mainly at the step of phosphorylation of glucose by hexokinase. Inhibition of this rate-limiting step by 2-DG causes a depletion of cellular ATP, leading to blockage of cell cycle progression and cell death in vitro.
CAS number 154-17-6
Molecular weight 164.16
Other name 2-Deoxy-D-arabinohexose, 2-Deoxyglucose
Molecular formula C₆H₁₂O₅
Physical appearance White to off-white solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% GC
Reconstitute instructions H2O (>15 mg/ml) or DMSO (>15 mg/ml)
Storage condition +4°C
Shipping condition gel pack
Maximum time for storage 36 months
Storage instructions Protect from air and moisture
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