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2 Deoxy D Glucose

2 Deoxy D Glucose is available 2 times from Biovision labs

B1048-500 | 2-Deoxy-D-Glucose size: 500 mg | 270.94 USD

Catalog number B1048-500
Supplier Biovision
Price 270.94 USD
Size 500 mg
1. Gene info
Identity 17226
Gene DGCR11
Long gene name DiGeorge syndrome critical region gene 11
Synonyms gene name
  • DiGeorge syndrome critical region gene 11
  • DiGeorge syndrome critical region gene 11 (non-protein coding)
Synonyms
  • DGS-D
GenBank acession
  • L77561
Locus 22q11.21
Discovery year 2002-11-13
Entrez gene record 25786
Pubmed identfication
  • 8776594
Classification
  • Long non-coding RNAs with non-systematic symbols
Havana BLAST/BLAT OTTHUMG00000186100
Product images
    #0#.jpeg2-Deoxy-D-Glucose

B1048-100 | 2-Deoxy-D-Glucose size: 100 mg | 121.98 USD

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Alternative_name 2-Deoxy-D-arabinohexose, 2-Deoxyglucose
Description 2-Deoxy-D-Glucose is a glucose analog that has long been known to act as a competitive inhibitor of glucose metabolism. Upon transport into the cells, 2-DG is phosphorylated by hexokinase to 2-DG-P. However, unlike G-6-P, 2-DG-P cannot be further metabolized by phosphohexose isomerase, which converts G-6-P to fructose-6-phosphate . 2-Deoxyglucose-P is trapped and accumulated in the cells, leading to inhibition of glycolysis mainly at the step of phosphorylation of glucose by hexokinase. Inhibition of this rate-limiting step by 2-DG causes a depletion of cellular ATP, leading to blockage of cell cycle progression and cell death in vitro.
CAS Number 154-17-6
Structure Available? Yes
Salt Form No
Molecular Formula C₆H₁₂O₅
Molecular Weight 164.16
Cell-Permeable? Yes
Purity ≥98% GC
Solubilities H2O (>15 mg/ml) or DMSO (>15 mg/ml)
Handling Protect from air and moisture
Tag Line A competitive inhibitor of glucose metabolism.
Storage Condition +4°C
Shipping Condition gel pack
Shelf Life 36 months
MDL Number MFCD00151328
PubChem CID 439268
SMILES C1C(C(C(OC1O)CO)O)O
InChi InChI=1S/C6H12O5/c7-2-4-6(10)3(8)1-5(9)11-4/h3-10H,1-2H2/t3-,4-,5?,6+/m1/s1
InChi Key PMMURAAUARKVCB-CERMHHMHSA-N
MSDS Available Yes
Gene target2-Deoxy-D-Glucose
Short name 2-Deoxy-D-Glucose
Alternative name 2-Deoxy-D-Glucose
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