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BRD3 Bromodomain1 29 145 aa His Tagged human recombinant

BRD3 Bromodomain1 29 145 aa His Tagged human recombinant is available 3 times from Biovision labs

7256-20 | BRD3-Bromodomain1 (29-145 aa) (His-Tagged) human recombinant size: 20 ug | 271.89 USD

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7256-100 | BRD3-Bromodomain1 (29-145 aa) (His-Tagged) human recombinant size: 100 ug | 711.66 USD

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7256-1000 | BRD3-Bromodomain1 (29-145 aa) (His-Tagged) human recombinant size: 1 mg | 5,389.65 USD

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Synonyms KIAA0043, RING3L
Alternative_names KIAA0043, RING3L
Description A protein involved in chromatin targeting
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥98%
Assay SDS-PAGE
Molecular Weight 16.2 kDa
Storage Temp. -80°C
Shipping Dry Ice
Shelf Life 12 months
Concentration 2 mg/ml
Appearance Liquid
Physical form description rh-BRD3-BD1 is supplied as a solution in PBS Buffer containing 10% glycerol
Background Information The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. BRD3 binds hyper-acetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. It regulates transcription by promoting the binding of the transcription factor GATA1 to its targets and transcription of the CCND1 gene. A chromosomal aberration involving BRD3 was found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. The recombinant protein includes Bromodomain-containing protein 3 (contains 29-145 aa) with N-terminal His-tag.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Conjugation histidine
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetBRD3-Bromodomain1 29-145 His-Tagged
Short name BRD3-Bromodomain1 (29-145 aa) (His-Tagged) recombinant
Technique Recombinant
Label his-tagged
Species Human
Alternative name BRD3-Bromodomain1 (29-145 aa) (histidine-Tagged) H. sapiens recombinant
Alternative technique rec
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BRD3 Bromodomain1 29 145 aa His Tagged human recombinant
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  • BRD3-Bromodomain1
  • 29-145
  • His-Tagged
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