MAGE-1 Antibody

• Catalog number
  GEN438253
• Price
  Please ask
• Size
  100ug

• Also known as
  MAGE-1
• Other names
  melanoma-associated antigen 1; Melanoma-associated antigen 1; melanoma-associated antigen 1; antigen MZ2-E; MAGE-1 antigen; melanoma antigen MAGE-1; cancer/testis antigen 1.1; melanoma antigen family A 1; melanoma-associated antigen MZ2-E; cancer/testis antigen family 1, member 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); Antigen MZ2-E; Cancer/testis antigen 1.1; CT1.1; MAGE-1 antigen
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  MAGEA1
• Gene name synonims
  N/A
• Other gene names
  MAGEA1; MAGEA1; CT1.1; MAGE1; MAGE1; MAGE1A; CT1.1
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  SPM282
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens), Rat (Rattus norvegicus), Dog.; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MAGE-1  
• Gene symbol
  MAGED4, MAGED2, MAGEA1, MAGEA4, TRO, MAGEB5, MAGEC2, MAGEB6, MAGEC3, MAGEB2
• Short name
  MAGE-1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-MAGE-1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:23793
• Gene
  MAGED4
• Long gene name
  MAGE family member D4
• Synonyms gene name
  • melanoma antigen family D4
• Synonyms
  • MAGE1
  • MGC3210
  • KIAA1859
  • MAGE-E1
• GenBank acession
  • AF320908
• Locus
  Xp11.22
• Discovery year
  2003-12-23
• Entrez gene record
  728239
• Pubmed identfication
  • 11406556
• RefSeq identity
  • NM_001098800
• Classification
  • MAGE family
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000042235

Gene info

• Identity
  HGNC:16353
• Gene
  MAGED2
• Long gene name
  MAGE family member D2
• Synonyms gene name
  • melanoma antigen family D2
• Synonyms
  • JCL-1
  • BCG1
  • 11B6
  • MAGE-D2
  • HCA10
  • MAGED
  • MGC8386
• Synonyms name
  • hepatocellular carcinoma associated protein
  • breast cancer associated gene 1
  • melanoma-associated antigen D2
  • hepatocellular carcinoma-associated protein HCA10
• GenBank acession
  • AF128527
• Locus
  Xp11.21
• Discovery year
  2001-08-16
• Entrez gene record
  10916
• RefSeq identity
  • NM_014599
• Classification
  • MAGE family
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000021638
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:6796
• Gene
  MAGEA1
• Long gene name
  MAGE family member A1
• Synonyms gene
  • MAGE1
• Synonyms gene name
  • melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
  • melanoma antigen family A1
• Synonyms
  • MGC9326
  • CT1.1
• Synonyms name
  • melanoma-associated antigen 1
  • melanoma-associated antigen MZ2-E
  • melanoma antigen MAGE-1
  • melanoma antigen family A 1
  • cancer/testis antigen family 1, member 1
• Locus
  Xq28
• Discovery year
  1994-04-04
• Entrez gene record
  4100
• Pubmed identfication
  • 1840703
  • 25590999
• RefSeq identity
  • NM_004988
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000024192
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:6802
• Gene
  MAGEA4
• Long gene name
  MAGE family member A4
• Synonyms gene
  • MAGE4
• Synonyms gene name
  • melanoma antigen family A4
• Synonyms
  • MAGE4A
  • MAGE4B
  • MAGE-41
  • MAGE-X2
  • MGC21336
  • CT1.4
• Synonyms name
  • melanoma-associated antigen 4
  • cancer/testis antigen family 1, member 4
• Locus
  Xq28
• Discovery year
  1994-04-04
• Entrez gene record
  4103
• Pubmed identfication
  • 8575766
• RefSeq identity
  • NM_002362
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000024174
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:12326
• Gene
  TRO
• Long gene name
  trophinin
• Synonyms
  • MAGE-D3
  • KIAA1114
  • MAGED3
• GenBank acession
  • U04811
• Locus
  Xp11.21
• Discovery year
  1997-10-30
• Entrez gene record
  7216
• Pubmed identfication
  • 9533028
  • 11454705
• RefSeq identity
  • NM_016157
• Classification
  • MAGE family
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000021640
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:23795
• Gene
  MAGEB5
• Long gene name
  MAGE family member B5
• Synonyms gene name
  • melanoma antigen family B5
• Synonyms
  • MAGE-B5
  • CT3.3
• Synonyms name
  • cancer/testis antigen family 3, member 3
• GenBank acession
  • AF333705
• Locus
  Xp21.3
• Discovery year
  2003-12-10
• Entrez gene record
  347541
• Pubmed identfication
  • 10861452
• RefSeq identity
  • NM_001271752
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000021288
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:13574
• Gene
  MAGEC2
• Long gene name
  MAGE family member C2
• Synonyms gene
  • MAGEE1
• Synonyms gene name
  • melanoma antigen, family E, 1, cancer/testis specific
  • melanoma antigen family C2
• Synonyms
  • CT10
  • MAGE-C2
  • HCA587
• Synonyms name
  • cancer/testis antigen 10
• GenBank acession
  • AF116195
• Locus
  Xq27.2
• Discovery year
  2000-09-26
• Entrez gene record
  51438
• Pubmed identfication
  • 10699956
  • 20864041
• RefSeq identity
  • NM_016249
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000022574
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:23796
• Gene
  MAGEB6
• Long gene name
  MAGE family member B6
• Synonyms gene name
  • melanoma antigen family B6
• Synonyms
  • FLJ40242
  • MAGE-B6
  • MAGEB6A
  • CT3.4
• Synonyms name
  • cancer/testis antigen family 3, member 4
• GenBank acession
  • AF320514
• Locus
  Xp21.3
• Discovery year
  2003-12-10
• Entrez gene record
  158809
• Pubmed identfication
  • 10861452
• RefSeq identity
  • NM_173523
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000021285
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:23798
• Gene
  MAGEC3
• Long gene name
  MAGE family member C3
• Synonyms gene name
  • melanoma antigen family C3
• Synonyms
  • HCA2
  • MAGE-C3
  • CT7.2
• Synonyms name
  • cancer/testis antigen family 7, member 2
• GenBank acession
  • AF490508
• Locus
  Xq27.2
• Discovery year
  2003-12-10
• Entrez gene record
  139081
• Pubmed identfication
  • 10861452
• RefSeq identity
  • NM_138702
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000022570
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:6809
• Gene
  MAGEB2
• Long gene name
  MAGE family member B2
• Synonyms gene name
  • melanoma antigen family B2
• Synonyms
  • DAM6
  • MAGE-XP-2
  • MGC26438
  • CT3.2
• Synonyms name
  • DSS/AHC critical interval MAGE superfamily 6
  • melanoma-associated antigen B2
  • cancer/testis antigen family 3, member 2
• GenBank acession
  • AF015766
• Locus
  Xp21.2
• Discovery year
  1997-08-15
• Entrez gene record
  4113
• Pubmed identfication
  • 9441743
• RefSeq identity
  • NM_002364
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000021319
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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