FGF-8, human recombinant

• Catalog number
  4053-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF
• Alternative_names
  Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF, Androgen-induced growth factor, Heparin-binding growth factor 8
• Description
  A heparin binding growth factor, stimulating the proliferation and activation of cells expressing FGFR
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Biological activity
  The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is 2 x 10⁶ units/mg.
• Molecular Weight
  22.4 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized in 10 mM Tris, pH 8.0 + 75 mM NaCl. The protein may appear as a haze or film, which may not be seen at the bottom of the vial.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.1-1 mg/ml. This solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Repeated freeze/thaw cycles will result in some loss of activity.
• Background Information
  Fibroblast Growth Factor-8 (FGF-8) is also known as Androgen-induced Growth Factor (AIGF), a heparin binding growth factor, which stimulates the proliferation and activation of cells that express the FGF receptors. Recombinant human FGF-8 is a 22.4 kDa protein containing 193 amino acid residues.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  FGF-8  
• Gene symbol
  FGF8, FGF18, FGF17, SNORD114-8, RNU6-8, SNORD113-8, SNORD116-8, IGKV2OR2-8, MIR1302-8, PIRC35
• Short name
  FGF-8, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  FGF-8, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:3686
• Gene
  FGF8
• Long gene name
  fibroblast growth factor 8
• Synonyms gene name
  • fibroblast growth factor 8 (androgen-induced)
• Synonyms
  • AIGF
• Synonyms name
  • androgen-induced growth factor
• GenBank acession
  • D38752
• Locus
  10q24.32
• Discovery year
  1995-08-15
• Entrez gene record
  2253
• Pubmed identfication
  • 8595889
• RefSeq identity
  • NM_006119
  • NM_033165
• Classification
  • Fibroblast growth factor family
  • Receptor ligands
• VEGA ID
  OTTHUMG00000018940

Gene info

• Identity
  HGNC:3674
• Gene
  FGF18
• Long gene name
  fibroblast growth factor 18
• Synonyms
  • FGF-18
  • ZFGF5
• GenBank acession
  • AB007422
• Locus
  5q35.1
• Discovery year
  1998-12-22
• Entrez gene record
  8817
• Pubmed identfication
  • 9660775
  • 9742123
• RefSeq identity
  • NM_033649
  • NM_003862
• Classification
  • Fibroblast growth factor family
• VEGA ID
  OTTHUMG00000130464

Gene info

• Identity
  HGNC:3673
• Gene
  FGF17
• Long gene name
  fibroblast growth factor 17
• Synonyms
  • FGF-13
• GenBank acession
  • AB009249
• Locus
  8p21.3
• Discovery year
  1998-12-22
• Entrez gene record
  8822
• Pubmed identfication
  • 9514906
  • 9751161
• RefSeq identity
  • NM_003867
• Classification
  • Fibroblast growth factor family
• VEGA ID
  OTTHUMG00000097051

Gene info

• Identity
  HGNC:32996
• Gene
  SNORD114-8
• Long gene name
  small nucleolar RNA, C/D box 114-8
• Synonyms
  • 14q(II-8)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767584
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003200.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:34285
• Gene
  RNU6-8
• Long gene name
  RNA, U6 small nuclear 8
• Synonyms
  • U6-8
• Locus
  14q12
• Discovery year
  2008-06-10
• Entrez gene record
  101954278
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104088
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:32987
• Gene
  SNORD113-8
• Long gene name
  small nucleolar RNA, C/D box 113-8
• Synonyms
  • 14q(I-8)
• Locus
  14q32.31
• Discovery year
  2006-09-20
• Entrez gene record
  767568
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003236.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33074
• Gene
  SNORD116-8
• Long gene name
  small nucleolar RNA, C/D box 116-8
• Synonyms
  • HBII-85-8
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033420
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003323
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5811
• Gene
  IGKV2OR2-8
• Long gene name
  immunoglobulin kappa variable 2/OR2-8 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-8
  • immunoglobulin kappa variable 2/OR2-8 pseudogene
• Synonyms
  • IGKV2/OR2-8
• GenBank acession
  • X51880
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  100996600
• RefSeq identity
  • NG_011662
• Classification
  • Immunoglobulin kappa (IGK) orphons

Gene info

• Identity
  HGNC:35300
• Gene
  MIR1302-8
• Long gene name
  microRNA 1302-8
• Synonyms gene
  • MIRN1302-8
• Synonyms
  • hsa-mir-1302-8
• Locus
  9q22.33
• Discovery year
  2008-11-03
• Entrez gene record
  100302223
• RefSeq identity
  • NR_031637
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37539
• Gene
  PIRC35
• Long gene name
  piwi-interacting RNA cluster 35
• Locus
  8
• Discovery year
  2009-11-05
• Entrez gene record
  100313855
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products