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Alternative_name
4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate; FUT-175; Futhan
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Description
A broad-spectrum, synthetic serine protease inhibitor and an inhibitor of the classical and alternative ways of complement activation. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma.
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CAS Number
82956-11-4
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₁₉H₁₇N₅O₂.2CH₄O₃S
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Molecular Weight
539.59
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Cell Permeable
Yes
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Purity
≥97% by HPLC
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Solubilities
DMSO (100 mM) and H₂O (100 mM)
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Handling
Protect from air and moisture
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Tag Line
A broad spectrum serine protease inhibitor
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
24 months
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MDL Number
MFCD00941430
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PubChem CID
5311180
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SMILES
CS(=O)(=O)O.CS(=O)(=O)O.C1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N
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InChi
InChI=1S/C19H17N5O2.2CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;2*1-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);2*1H3,(H,2,3,4)
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InChi Key
SRXKIZXIRHMPFW-UHFFFAOYSA-N
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MSDS Available
Yes
