Filters
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing
Ajax processing

LY364947 for cell activation

LY364947 for cell activation is available 2 times from Biovision labs

2646-1 | LY364947 for cell activation size: 1 mg | 150.84 USD

Loading

2646-5 | LY364947 for cell activation size: 5 mg | 411.37 USD

Loading
Other name 4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-quinoline; HTS 466284
Supplied with N/A
Description LY364947 is a selective inhibitor of TGF-β RI (TGFR-I, TβR-I, ALK-5), with an IC₅₀ value of 59 nM. LY364947 only weakly inhibits TGF-β RII (IC₅₀ = 400 nM), p38 MAPK (IC₅₀ = 740 nM), and mixed lineage kinase-7 (MLK-7; IC₅₀ = 1,400 nM).It inhibits TGF-β-induced cell growth (IC₅₀ = 89 nM) in NIH 3T3 mouse fibroblasts and TGF-β-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells.
Category Biochemicals
Molecular formula C₁₇H₁₂N₄
Is it cell-permeable? Yes
Molecular weight 272.31
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 396129-53-6
Storage instructions Protect from air and light
Maximum time for storage 48 months
Physical appearance Off-white solid
Reconstitute instructions DMSO (~ 25 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetLY364947 for activation
Short name LY364947 for activation
Technique activation
Alternative name LY364947 to measure cellular activation
Tissue cell
Similar products
Delamanid for cell activation Suppplier: Biovision
Price: 261.68 USD
Gardiquimod for cell activation Suppplier: Biovision
Price: 156.55 USD
PF 04691502 for cell activation Suppplier: Biovision
Price: 274.25 USD
GW788388 for cell activation Suppplier: Biovision
Price: 237.68 USD
K858 for cell activation Suppplier: Biovision
Price: 225.11 USD
CID 1067700 for cell activation Suppplier: Biovision
Price: 225.11 USD
RAD140 for cell activation Suppplier: Biovision
Price: 212.54 USD
VU0361737 for cell activation Suppplier: Biovision
Price: 199.97 USD
GW 0742 for cell activation Suppplier: Biovision
Price: 212.54 USD
(-)-JQ1 for cell activation Suppplier: Biovision
Price: 212.54 USD
DTT for cell activation Suppplier: Biovision
Price: 143.98 USD
PX 866 for cell activation Suppplier: Biovision
Price: 143.98 USD
EPZ011989 for cell activation Suppplier: Biovision
Price: 261.68 USD
Flavopiridol for cell activation Suppplier: Biovision
Price: 169.12 USD
PD 150.606 for cell activation Suppplier: Biovision
Price: 156.55 USD
Jervine for cell activation Suppplier: Biovision
Price: 212.54 USD
Fexaramine for cell activation Suppplier: Biovision
Price: 212.54 USD
P7C3 A20 for cell activation Suppplier: Biovision
Price: 199.97 USD
Ask
Ajax processing
Close
LY364947 for cell activation - Gentaur.com
Filters
+32-(0)1-658-90-45 lieven@gentaur.com
Contact us
Ajax processing
Close
Chat with gentaur.com employee