trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane, L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatine, N-(trans-Epoxysuccinyl)-L-leucine 4-guanidinobutylamide
E-64 is an irreversible, cell-permeable, potent, and highly selective cysteine protease inhibitor. E-64 will not inhibit serine proteases (except trypsin) like other cysteine protease inhibitors, leupeptin and antipain. A very useful cysteine protease inhibitor for use in in vivo studies because it has a specific inhibition and displays low toxicity.
Is it cell-permeable?
≥99% by HPLC
Is this a salt?
Protect from air and moisture
Maximum time for storage
White crystalline solid
DMSO (25 mg/ml) or H₂O (20 mg/ml)
For cells, cell lines and tissues in culture till half confluency.