TLR5 Antibody

• Catalog number
  R31826
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  TLR5
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  Optimal dilution of the TLR5 antibody should be determined by the researcher.
• Intented use
  This TLR5 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O60602
• Purity
  Antigen affinity
• Description
  TLR5 encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
• Immunogen
  Amino acids MKHQSIRGFVQKQQYLRWPEDFQDVGWF of human TLR5 were used as the immunogen for the TLR5 antibody.
• Storage
  After reconstitution, the TLR5 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic, membrane
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR5  
• Gene symbol
  TLR5
• Short name
  Anti-TLR5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to TLR5
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 5, MELIOS and SLE1 and SLEB1 and TIL3, TLR5 and IDBG-106840 and ENSG00000187554 and 7100, protein binding, Plasma membranes, Tlr5 and IDBG-259066 and ENSMUSG00000079164 and 53791, TLR5 and IDBG-648348 and ENSBTAG00000000477 and 444870

Gene info

• Identity
  HGNC:11851
• Gene
  TLR5
• Long gene name
  toll like receptor 5
• Synonyms gene
  • SLEB1
• Synonyms gene name
  • systemic lupus erythematosus susceptibility 1
  • toll-like receptor 5
• Synonyms
  • TIL3
  • FLJ10052
  • MGC126430
  • MGC126431
• Synonyms name
  • Toll/interleukin-1 receptor-like protein 3
• Locus
  1q41
• Discovery year
  1998-06-25
• Entrez gene record
  7100
• Pubmed identfication
  • 9435236
  • 16027372
• RefSeq identity
  • NM_003268
• Classification
  • Toll like receptors
• VEGA ID
  OTTHUMG00000037937

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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