(5Z,9Z,13Z)-Geranylgeranylacetone

  • Catalog number
    G367530
  • Price
    Please ask
  • Size
    10 mg
  • Chemical available in other sizes
    Please inquire size and price
  • Stock availability
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  • Cas number
    3796-67-6
  • Chemical s molecular weight
    330.55
  • Chemical s main applications
    (5Z,9Z,13Z)-Geranylgeranylacetone is the structural analogue of Teprenone (T103500), an anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
  • Chemical s category
    Aliphatics, Pharmaceuticals, Intermediates & Fine Chemicals
  • Other name
    (5Z,9Z,13Z)-6,10,14,18-Tetramethylnonadeca-5,9,13,17-tetraen-2-one; all-Z-Geranylgeranylacetone
  • Chemical s formula
    C23H38O
  • Physical properties
    No Data Available
  • Melting temperature
    No Data Available
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    No Data Available
  • Stability conditions
    No Data Available
  • Storage
    No Data Available
  • Gene target
  • Short name
    (5Z 9Z 13Z)-Geranylgeranylacetone
  • Alternative name
    (5Z,9Z,13Z)-Geranylgeranylacetone
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