(5Z,9Z,13Z)-Geranylgeranylacetone
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Catalog number
G367530
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Price
Please ask
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Size
10 mg
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Chemical available in other sizes
Please inquire size and price
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Stock availability
Please Inquire
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Cas number
3796-67-6
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Chemical s molecular weight
330.55
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Chemical s main applications
(5Z,9Z,13Z)-Geranylgeranylacetone is the structural analogue of Teprenone (T103500), an anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
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Chemical s category
Aliphatics, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
(5Z,9Z,13Z)-6,10,14,18-Tetramethylnonadeca-5,9,13,17-tetraen-2-one; all-Z-Geranylgeranylacetone
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Chemical s formula
C23H38O
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Physical properties
No Data Available
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Melting temperature
No Data Available
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Boiling temperature
No Data Available
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Chemical s soluble in
No Data Available
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Stability conditions
No Data Available
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Storage
No Data Available
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Gene target
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Short name
(5Z 9Z 13Z)-Geranylgeranylacetone
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Alternative name
(5Z,9Z,13Z)-Geranylgeranylacetone
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