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Gambogic acid for cell activation

Gambogic acid for cell activation is available 2 times from Biovision labs

2785-5 | Gambogic acid for cell activation size: 5 mg | 198.56 USD

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2785-25 | Gambogic acid for cell activation size: 25 mg | 618.36 USD

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Other name  (Z)-4-((1S,3aR,5S,11R,14aS)-8-hydroxy-2,2,11-trimethyl-13-(3-methylbut-2-en-1-yl)-11-(4-methylpent-3-en-1-yl)-4,7-dioxo-2,3a,4,5,7,11-hexahydro-1H-1,5-methanofuro[3,2-g]pyrano[3,2-b]xanthen-3a-yl)-2-methylbut-2-enoic acid
Supplied with N/A
Description Gambogic acid is a plant-derived natural product that acts as a caspase activator and apoptosis inducer, which causes an irreversible arrest in the G2/M phase of the cell cycle. It causes a decrease of Bcl-2 gene and an increase in Bax gene expression, which may result in apoptosis. Gambogic also acts as an inhibitor of A1 and Bcl-2 family proteins, including Bcl-xl, Bcl-2, Bcl-w, Bcl-B, Bfl-1, and Mcl-1.
Category Biochemicals
Molecular formula C₃₈H₄₄O₈
Is it cell-permeable? Y
Molecular weight 628.75
Storage condition -20°C
Shipping condition Gel Pack
Purification ≥95%
Peptide sequence N/A
Is this a salt? No
CAS number 2752-65-0
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Orange solid
Reconstitute instructions DMSO (>25 mg/ml) or EtOH (~20 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name Gambogic acid for activation
Technique activation
Alternative name Gambogic acid to measure cellular activation
Tissue cell
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