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anti-SIRT6 Antibody

anti-SIRT6 Antibody is available 1 time from Biovision labs

6692-100 | anti-SIRT6 Antibody size: SIRT6 Antibody | 395.60 USD

Catalog number 6692-100
Supplier Biovision
Price 395.60 USD
Size SIRT6 Antibody
1. Gene info
Identity 14934
Gene SIRT6
Long gene name sirtuin 6
Synonyms gene name
  • sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6
  • sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
GenBank acession
  • AF233396
Locus 19p13.3
Discovery year 2001-03-20
Entrez gene record 51548
Pubmed identfication
  • 10873683
Classification
  • Sirtuins
Havana BLAST/BLAT OTTHUMG00000181847
Product images
    #0#.jpegSIRT6 Antibody
Target of this antibody: SIRT6
Alternative names of antibody target: SIRT6, NAD-dependent Deacetylase Sirtuin-6; Mono-ADP-ribosyltransferase Sirtuin 6; SIR2-like Protein 6; SIR2L6
Background information: Human Sirtuins function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards Lys-9 and Lys-56 of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-α.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, Mouse
Immunogene sequence: Recombinant Human Sirtuin 6 (Cat # 7699)
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.
Purification method: Affinity Purified Antibody
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blot: 1-4 µg
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetSIRT6
Short name anti-SIRT6 Antibody
Technique Antibody, anti
Alternative name antibody to-SIRT6 (Antibody to)
Alternative technique antibodies
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anti-SIRT6 Antibody | Technique alternative | 01012194149
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