HG-9-91-01

• Catalog number
  B1849-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (Z)-N-(2,4-dimethoxyphenyl)-N'-(2,6-dimethylphenyl)-N-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)carbamimidic acid
• Description
  HG-9-91-01 is a potent, selective, ATP-competitive, pan-SIK (salt-inducible kinases) inhibitor with IC₅₀ values of 0.92 nM, 6.6n M and 9.6 nM for SIK1, SIK2, SIK3, respectively.
• CAS Number
  1456858-58-4
• Structure Available
  Yes
• Molecular Formula
  C₃₂H₃₇N₇O₃
• Molecular Weight
  567.68
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent, selective, ATP-competitive, pan-SIK (salt-inducible kinases) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  78357808
• PubChem CID Link
• SMILES
  CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
• InChi
  InChI=1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-14,19-21H,15-18H2,1-5H3,(H,36,40)(H,33,34,35)
• InChi Key
  UYUHRKLITDJEHB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  HG-9-91-01  
• Gene symbol
  HCG4P1, MRPS2, RNU6-9, PIRC47, PIRC38, PIRC43, PIRC45
• Short name
  HG-9-91-01
• Alternative name
  HG-9-91-01

Gene info

• Identity
  HGNC:30978
• Gene
  HCG4P1
• Long gene name
  HLA complex group 4 pseudogene 1
• Synonyms
  • HCGIV-01
• Locus
  6p21.3
• Discovery year
  2003-12-16
• Entrez gene record
  387503

Gene info

• Identity
  HGNC:14495
• Gene
  MRPS2
• Long gene name
  mitochondrial ribosomal protein S2
• Synonyms
  • CGI-91
• GenBank acession
  • AB051627
• Locus
  9q34.3
• Discovery year
  2001-01-26
• Entrez gene record
  51116
• Classification
  • Mitochondrial ribosomal proteins
  • Small subunit mitochondrial ribosomal proteins
• VEGA ID
  OTTHUMG00000020910

Gene info

• Identity
  HGNC:34269
• Gene
  RNU6-9
• Long gene name
  RNA, U6 small nuclear 9
• Synonyms
  • U6-9
• Locus
  19p13.3
• Discovery year
  2008-06-10
• Entrez gene record
  101954271
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104080
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:37551
• Gene
  PIRC47
• Long gene name
  piwi-interacting RNA cluster 47
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313859
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37542
• Gene
  PIRC38
• Long gene name
  piwi-interacting RNA cluster 38
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313788
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37547
• Gene
  PIRC43
• Long gene name
  piwi-interacting RNA cluster 43
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313857
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37549
• Gene
  PIRC45
• Long gene name
  piwi-interacting RNA cluster 45
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313813
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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