Human CellExp™ EPO, Human Recombinant
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Catalog number
6447-10
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Price
Please ask
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Size
10 ug
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Synonyms
Human Cellexp Human Recombinant EPO
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Alternative_names
Erythropoietin-Alpha, EPO-a, EPO-alpha, Epoetin, EP, MGC138142.
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Description
A glycoprotein hormone that controls erythropoiesis
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Recombinant
Yes
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Source
Human 293 cell expressed
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Endotoxin Level
< 1.0 EU per 1 ug of protein
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Biological activity
ED₅₀ is typically 0.5 to 2.5 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).
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Results
0.5 to 2.5 ng/ml
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Molecular Weight
36 kDa, monomer, glycosylated
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Storage Temp
-20°C
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Shipping
gel pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Physical form description
Lyophilized from a PBS solution.
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Reconstitution Instructions
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
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Background Information
Erythropoietin is a member of the EPO/TPO family. EPO is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
EPO, TIMP1, EPX
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Short name
CellExp™ EPO, Recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Humans
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Alternative name
H. sapiens CellExp™ erythropoietin, H. sapiens Rec.
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Alternative technique
rec
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Alternative to gene target
erythropoietin, EP and MVCD2, EPO and IDBG-31941 and ENSG00000130427 and 2056, protein kinase activator activity, Extracellular, Epo and IDBG-205003 and ENSMUSG00000029711 and 13856, EPO and IDBG-640493 and ENSBTAG00000003430 and 280784
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Gene info
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Identity
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Gene
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Long gene name
erythropoietin
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
eosinophil peroxidase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-11-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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