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Synonyms
DPPIV, DPP4, Dipeptidylpeptidase-4
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Alternative_names
CD26, ADABP, ADCP2, DPPIV, TP103, DPP4, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, Adenosine deaminase complexing protein 2, CD26 antigen.
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Description
An antigenic enzyme associated with immune regulation, signal transduction and apoptosis.
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Recombinant
No
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Source
Human Placenta
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Molecular Weight
350.0 kDa
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Storage Temp
-70°C
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Shipping
Dry ice
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Shelf Life
12 months
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Appearance
Liquid
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Physical form description
Frozen liquid in 2 mM Tris-HCl, pH 8.0.
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Background Information
Dipeptidyl Peptidase IV is a lymphocyte cell surface antigen which is increased during T-cell activation and is also expressed in other tissues, such as placenta, kidney, etc. It is an atypical serine protease which has been implicated in a variety of biological functions including diabetes, rheumatoid arthritis, T-cell activation, cell-to-cell adhesion, and recently in HIV infection.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
