IL-32 alpha, human recombinant
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Catalog number4189-1000
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PricePlease ask
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Size1 mg
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SynonymsNK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, IL-32β, IL-32α, IL-32delta, IL-32γ, Interleukin-32, IL-32, Natural killer cells protein 4, Tumor necrosis factor α-inducing factor, IL-32a, IL32a, IL32, Interleukin-32 α.
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Alternative_namesNK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, IL-32β, IL-32α, IL-32delta, IL-32γ, Interleukin-32, IL-32, Natural killer cells protein 4, Tumor necrosis factor α-inducing factor, IL-32a, IL32a, IL32, Interleukin-32 α.
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DescriptionA cytokine that induces immune cells to secrete TNF-α
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥97%
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AssaySDS-PAGE
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Biological activityHuman IL-32 α activity is measured via the dose-dependent induction of TNF-α in the human THP-1 monocytic cell line.
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Molecular Weight14.9 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionLyophilized from 50 mM NaP, pH 7.5.
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Reconstitution InstructionsIt is recommended to reconstitute the lyophilized product with sterile H₂O at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
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Background InformationHuman IL-32 α is one of approximately 6 splice variants of a gene cloned from the human lung carcinoma stable transfectant, A549-Rβ. IL-32 α has been shown to induce IL-8, TNF-α, and MIP-2 production from human & mouse macrophage cell lines. It is up-regulated in activated T- & NK-cells, and IFN-γ-treated epithelial cells. Human recombinant IL-32 α produced in E. coli is a 131 amino acid non-glycosylated polypeptide with a molecular mass of 14.9 kDa.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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Additional descriptionThe IL-32 alpha, recombinant is a α- or alpha protein sometimes glycoprotein present in blood.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolIGKV1D-32, SNORD115-32, PPP1R1B, IGHV3-32, IGKV1-32, IGLV3-32, ZNF138, CUTC, IL36G, IL32
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Short nameIL-32 alpha, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameInterleukin-32 a, H. sapiens Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1D-32 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 1D-32
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa locus at 2p11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-32
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameprotein phosphatase 1 regulatory inhibitor subunit 1B
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Synonyms gene name
- protein phosphatase 1, regulatory (inhibitor) subunit 1B
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-01-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 3-32 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable 3-32
- immunoglobulin heavy variable 3-32 pseudogene
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1-32 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 1-32
- immunoglobulin kappa variable 1-32 pseudogene
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa locus at 2p11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable 3-32 (non-functional)
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Synonyms gene name
- immunoglobulin lambda variable 3-32
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namezinc finger protein 138
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Synonyms gene name
- zinc finger protein 138 (clone pHZ-32)
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-02-11
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Entrez gene record
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecutC copper transporter
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Synonyms gene name
- cutC copper transporter homolog (E. coli)
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-04-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 gamma
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 32
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-02-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
