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PEDF human recombinant

PEDF human recombinant is available 3 times from Biovision labs

4988-1000 | PEDF, human recombinant size: 1 mg | 5,479.33 USD

Catalog number 4988-1000
Supplier Biovision
Price 5,479.33 USD
Size 1 mg
1. Gene info
Identity 8824
Long gene name serpin family F member 1
Synonyms gene
  • PEDF
Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
  • pigment epithelium-derived factor
  • EPC-1
  • PIG35
Synonyms name
  • alpha-2 antiplasmin
  • proliferation-inducing protein 35
GenBank acession
  • M76979
Locus 17p13.3
Discovery year 1993-05-18
Entrez gene record 5176
Pubmed identfication
  • 8434014
  • 24172014
RefSeq identity
  • NM_002615
  • Serpin peptidase inhibitors
Havana BLAST/BLAT OTTHUMG00000090571
Locus Specific Databases
  • SERPINF1 variant database
2. Gene info
Identity 14227
Long gene name ERBB receptor feedback inhibitor 1
  • MIG-6
  • GENE-33
  • RALT
  • [HGNC:8824](/data/gene-symbol-report/#!/hgnc_id/HGNC:8824)
  • ERRFI1
GenBank acession
  • BC025337
Locus 1p36.23
Discovery year 2005-08-23
Entrez gene record 54206
Pubmed identfication
  • 10749885
  • 2780291
  • 12226756
  • 11003669
RefSeq identity
  • NM_018948
Havana BLAST/BLAT OTTHUMG00000001221
Product images
    #Human#.jpg#0#.jpegPEDF, human recombinant

4988-100 | PEDF, human recombinant size: 100 ug | 866.19 USD


4988-20 | PEDF, human recombinant size: 20 ug | 309.83 USD

Synonyms Pigment epithelium-derived factor, PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35
Alternative_names Pigment epithelium-derived factor, PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35
Description A multifunctional protein with anti-angiogenic, anti-tumorigenic, and neurotrophic functions
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥95%
Purity ≥95%
Biological activity Not available at this time
Molecular Weight 44.5 kDa
Storage Temp. -20°C
Shipping Blue ice
Shelf Life 12 months
Appearance Lyophilized protein
Physical form description The sterile filtered concentrated (1 mg/ml) protein solution was lyophilized with 20 mM PBS & 150 mM NaCl pH-7.4.
Reconstitution Instructions The sterile filtered concentrated (1 mg/ml) protein solution was lyophilized with 20 mM phosphate buffer & 150 mM NaCl pH-7.4.
Background Information PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. PEDF is a 50,000 dalton glycoprotein created and secreted in many tissues all the way through the body. A key component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. Additionally, PEDF is capable to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The recognition of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. The unique range of PEDF activities associate it as a potential therapeutic agent for the treatment of vasculature related neurodegenerative diseases such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR). PEDF in addition has the potential to be functional in the treatment of various angiogenesis-related diseases including a number of cancers. Recombinant human PEDF produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 400 amino acids and having a molecular mass of 44.5 kDa.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetPEDF
Short name PEDF, recombinant
Technique Recombinant
Species Human
Alternative name PEDF, H. sapiens recombinant
Alternative technique rec
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PEDF, recombinant | Technique alternative | 01012195828
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • PEDF
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