p, WAF-1

Available ordering format

Liquid
Immunogen

Human p21 protein. UniProt: P38936
Raised in

Mouse
Clonality

Monoclonal
Clone

WA-1, IgG1
Purification

Protein A/G purified.
How to reconstitute

See included datasheet or contact our support service
Storage condition

Store at -20°C.
Verified applications

ELISA (ELISA), Western Blot (WB)
Connected products

anti-mouse secondary antibodies
Recommended dilutions for use

1-10 µg/ml (WB), optimal concentrations should be determined by serial dilutions.
Molecular weight expected аpparent

see datasheet
Verified reactivity

Human
Possible reactivity

to be determined
No reactivity

No confirmed exceptions from predicted reactivity known at the moment.
Supplementary information

Contact Gentaur support center at [email protected]
References

To be added when available, antibody released in November 2016.
Scientific context

The expression of p21 is mostly induced by p53, usually in response to DNA damage induced by cytotoxic agents. p21 interrupts the cell cycle and prevents the replication of the cell containing genomic errors. p21 also inhibits Cdk2, Cdk3, Cdk4 and Cdk6 to stop the cell cycle. Alternative names: Cyclin-dependent kinase inhibitor 1
Notes

Provided in phosphate buffered saline, contains 0.08% sodium azide.Detects a 21 kDa protein in MCF7 cells. Can be used with either frozen or paraffin embedded tissue sections.
Protein number

P38936
TAIR number

Refer to NCBI
Hyperlink

Gene target

WAF-1
Gene symbol

CDKN1A, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1, MIR16-1
Short name

p, WAF-1
Alternative name

p, WAF-1

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081