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AKR1B10 human recombinant

AKR1B10 human recombinant is available 2 times from Biovision labs

6339-1000 | AKR1B10, human recombinant size: 1 mg | 1,736.95 USD

Catalog number 6339-1000
Supplier Biovision
Price 1,736.95 USD
Size 1 mg
1. Gene info
Identity 382
Gene AKR1B10
Long gene name aldo-keto reductase family 1 member B10
Synonyms gene
  • AKR1B11
Synonyms gene name
  • aldo-keto reductase family 1, member B10 (aldose reductase)
Synonyms
  • AKR1B12
  • ARL-1
  • HIS
  • ARL1
  • HSI
  • ALDRLn
Synonyms name
  • aldose reductase-like 1
  • aldo-keto reductase family 1, member B11 (aldose reductase-like)
  • aldose reductase-like peptide
  • aldose reductase-related protein
  • small intestine reductase
GenBank acession
  • AF052577
Locus 7q33
Discovery year 2000-08-24
Entrez gene record 57016
Pubmed identfication
  • 9765596
  • 9565553
RefSeq identity
  • NM_020299
Classification
  • Aldo-keto reductases
Havana BLAST/BLAT OTTHUMG00000155356
Product images
    #Human#.jpg#0#.jpegAKR1B10, human recombinant

6339-100 | AKR1B10, human recombinant size: 100 ug | 502.41 USD

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Synonyms Aldo-keto reductase family 1, member B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HIS.
Alternative_names Aldo-keto reductase family 1, member B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HIS.
Description Involved in in the detoxification of aldehydes and ketones
Recombinant Yes
Source E. coli
Purity by SDS-PAGE ≥98%
Assay SDS-PAGE
Biological activity The specific activity of AKR1B10 with 5 mM glyceraldehyde is approximately ~100 mU/mg. (Specific activity is calculated by the decrease of absorption at 340 nm in presence of 2-10 µg AKR1B10, 5mM glyceraldehyde, 200 µM NADPH in 0.1 M sodium phosphate buffer, pH 7.5).
Results ~100 mU/mg
Unit Definition One unit is the amount of enzyme that oxidizes 1.0 µmole of NADPH to NADP+ per min. at pH 7.5 at 25°C.
Molecular Weight 36 kDa
Storage Temp. -20°C
Shipping gel pack
Shelf Life 12 months
Concentration 1 mg/ml
Appearance Liquid
Physical form description 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol.
Background Information AKR1B10 is a monomeric protein that efficiently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is ubiquitously expressed in many human tissues but is highly expressed in small intestine, colon and adrenal gland. This protein is pathogenically involved in diabetic complications. It has been reported that AKR1B10 is overexpressed in human tumors, such as liver, breast, and lung cancer, and may play a critical role in the development and progression of cancer.
Amino acid sequence MATFVELSTK AKMPIVGLGT WKSPLGKVKE AVKVAIDAGY RHIDCAYVYQ NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL KLSYLDVYLI HWPQGFKSGD DLFPKDDKGN AIGGKATFLD AWEAMEELVD EGLVKALGVS NFSHFQIEKL LNKPGLKYKP VTNQVECHPY LTQEKLIQYC HSKGITVTAY SPLGSPDRPW AKPEDPSLLE DPKIKEIAAK HKKTAAQVLI RFHIQRNVIV IPKSVTPARI VENIQVFDFK LSDEEMATIL SFNRNWRACN VLQSSHLEDY PFDAEY
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetAKR1B10
Short name AKR1B10, recombinant
Technique Recombinant
Species Human
Alternative name AKR1B10, H. sapiens recombinant
Alternative technique rec
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AKR1B10, recombinant | Technique alternative | 01012195988
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