Recombinant Oryza sativa subsp. japonica Protein LSD1 (LSD1)

  • Catalog number
    MBS1370362
  • Price
    Please ask
  • Size
    1 mg (Yeast)
  • Products_type
    Recombinant Protein
  • Products_short_name
    [Protein LSD1 (LSD1)]
  • Other_names
    [protein LSD1 isoform X2; Protein LSD1; protein LSD1; Protein LESION SIMULATING DISEASE 1; OsLSD1; Putative zinc finger LSD1]
  • Products_gene_name
    [LSD1]
  • Products_gene_name_syn
    [LSD1]
  • Other_gene_names
    [LOC4344713; LSD1; LSD1; OsLSD1; OsJ_26122; OsLSD1]
  • Purity
    >85% (SDS-PAGE)
  • Form
    Lyophilized or liquid (Format to be determined during the manufacturing process)
  • Storage_stability
    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
  • Gene
    Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, was belonged to the superfamily of the Flavin adenine dinucleotide (FAD)-dependent amine oxidases. LSD1 specifically demethylates mono- or dimethylated dimethylated histone H3 lysine4 (H3K4) and H3 lysine 9 (H3K9) via a redox process. Recently evidences showed that LSD1 played an important role in a broad spectrum of biological processes, including cell proliferation, adipogenesis, spermatogenesis, chromosome segregation and embryonic development. Furthermore, LSD1 also could promote progress of tumor by inhibiting the tumor suppressor activity of p53. To date, as a potential drug for discovering anti-tumor drugs, the medical significance of LSD1 inhibitors have been greatly appreciated. Here, we reviewed the remarkable progress being made in understanding of LSD1, mainly on its structure, basic function and medical application in tumor therapy.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    Oryza   sativa   subsp   japonica   Protein   LSD1   LSD1  
  • Gene symbol
    KDM1A
  • Short name
    Recombinant Oryza sativa subsp. japonica Protein LSD1 (LSD1)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Host
    E Coli or Yeast or Baculovirus or Mammalian Cell
  • Alternative name
    Rec. Oryza sativa subsp. japonica Protein LSD1 (LSD1)
  • Alternative technique
    rec
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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