CD33 Antibody

• Catalog number
  GEN438501
• Price
  Please ask
• Size
  100ug

• Also known as
  CD33
• Other names
  myeloid cell surface antigen CD33 isoform 2; Myeloid cell surface antigen CD33; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; CD33 molecule; Sialic acid-binding Ig-like lectin 3; Siglec-3; gp67; CD_antigen: CD33
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CD33
• Gene name synonims
  N/A
• Other gene names
  CD33; CD33; p67; SIGLEC3; SIGLEC-3; SIGLEC3; Siglec-3
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  C33/68
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes a 67kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies, Immunoprecipitation (IP), Immunohistology (IH)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD33  
• Gene symbol
  CD33
• Short name
  CD33 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-CD33
• Alternative technique
  antibodies
• Alternative to gene target
  CD33 molecule, p67 and SIGLEC-3 and SIGLEC3, CD33 and IDBG-65737 and ENSG00000105383 and 945, protein binding, Cell surfaces

Gene info

• Identity
  HGNC:1659
• Gene
  CD33
• Long gene name
  CD33 molecule
• Synonyms gene name
  • CD33 antigen (gp67)
• Synonyms
  • SIGLEC3
  • SIGLEC-3
  • p67
  • FLJ00391
• Synonyms name
  • sialic acid binding Ig-like lectin 3
• GenBank acession
  • M23197
• Locus
  19q13.41
• Discovery year
  1986-01-01
• Entrez gene record
  945
• Pubmed identfication
  • 3139766
  • 9465907
• RefSeq identity
  • NM_001772
• Classification
  • CD molecules
  • Sialic acid binding Ig like lectins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000182891

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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