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Also known as
GHRL / Ghrelin
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Other names
appetite-regulating hormone isoform 1 preproprotein; Appetite-regulating hormone; appetite-regulating hormone; motilin-related peptide; ghrelin/obestatin preprohormone; growth hormone-releasing peptide; prepro-appetite regulatory hormone; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin prepropeptide; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; Protein M46Cleaved into the following 3 chains:Ghrelin-27; Ghrelin-28; Ghrelin; Obestatin
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
GHRL
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Gene name synonims
N/A
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Other gene names
GHRL; GHRL; MTLRP; MTLRP; Ghrelin
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG2a,k
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Clone
2F4
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Human GHRL; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Protein A Purified
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Form Appearance
PBS, pH 7.2
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Concentration
0.5 mg/ml
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Storage and shipping
Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
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Tested applications
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Description
Ghrelin, GHRL gene, obestatin prepropeptide or lenomorelin from ghrelinergic cells in the gastrointestinal tract. GHRL is a neuropeptide in the central nervous system regulating appetite. Ghrelin is regulating the distribution and rate of use of body energy.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
GHRL, GHRLOS, LINC00852
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Short name
Mouse Monoclonal [clone 2F4] (IgG2a k) GHRL / Ghrelin Antibody
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Technique
Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG2a
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Species
Human, Humans, Mouses
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Alternative name
Anti-Mouse Monoclonal [clone 2F4] (IgG2a,k) to Human GHRL / Ghrelin
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Alternative technique
antibodies, murine
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Alternative to gene target
ghrelin/obestatin prepropeptide, GHRL and IDBG-18011 and ENSG00000157017 and 51738, ghrelin receptor binding, Extracellular, Ghrl and IDBG-178411 and ENSMUSG00000064177 and 58991, GHRL and IDBG-646311 and ENSBTAG00000012328 and 281192
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Clone name
2F4
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