Mouse Monoclonal [clone 2-22] (IgG1) to Human CASP9 / Caspase 9

• Catalog number
  MBS245551
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [CASP9 / Caspase 9]
• Products_name_syn
  [Anti-CASP9 / Caspase 9 Antibody (clone 2-22) IHC-plus; CASP9; APAF3; CASPASE-9c; ICE-LAP6; MCH6; ICE-like apoptotic protease 6; APAF-3; Apoptotic protease Mch-6; CASP-9; Caspase 9; Caspase-9; PPP1R56; Human CASP9; Caspase 9]
• Other_names
  [caspase-9 isoform alpha; Caspase-9; caspase-9; apoptotic protease MCH-6; ICE-like apoptotic protease 6; apoptotic protease activating factor 3; protein phosphatase 1, regulatory subunit 56; caspase 9, apoptosis-related cysteine peptidase; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6]
• Products_gene_name
  [CASP9]
• Other_gene_names
  [CASP9; CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; MCH6; CASP-9; APAF-3; ICE-LAP6]
• Clonality
  Monoclonal
• Clone
  [2-22]
• Reactivity
  Human, Monkey
• Specificity
  Detects an ~46-50 kD protein, corresponding to the apparent molecular mass of the caspase-9 on SDS-PAGE immunoblots, in samples from human and monkey origins. This antibody recognizes the pro-caspase-9 human recombinant protein as well as pro-caspase -9 from human and monkey cell lysates.
• Purity
  Protein G Purified
• Form
  PBS, 0.01 mM PMSF, 50% glycerol
• Concentration
  1 mg/ml
• Storage_stability
  Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
• Tested_application
  Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP)
• Description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• Gene
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Monoclonal   2-22]   IgG1   CASP9   Caspase  
• Gene symbol
  IGHVIII-22-2, SNORD114-22, PIRC112, PIRC111, PIRC108, PIRC109, VN1R112P, PIRC107, PIRC110, PIRC106
• Short name
  Mouse Monoclonal [clone 2-22] (IgG1) CASP9 / Caspase 9
• Technique
  Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1, IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse monoclonal [clonality 2-22] (IgG1) to H. sapiens caspase 9, apoptosis-related cysteine peptidase / caspase 9
• Alternative technique
  murine
• Alternative to gene target
  caspase 9, apoptosis-related cysteine peptidase, APAF-3 and APAF3 and ICE-LAP6 and MCH6 and PPP1R56, CASP9 and IDBG-90895 and ENSG00000132906 and 842, protein kinase binding, nuclei, Casp9 and IDBG-202405 and ENSMUSG00000028914 and 12371, CASP9 and IDBG-635833 and ENSBTAG00000002472 and 100140945
• Clone name
  2-22

Gene info

• Identity
  HGNC:5696
• Gene
  IGHVIII-22-2
• Long gene name
  immunoglobulin heavy variable (III)-22-2 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (III)-22-2
  • immunoglobulin heavy variable (III)-22-2 pseudogene
• Synonyms
  • IGHV(III)-22-2
• GenBank acession
  • AB019439
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28349
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152060

Gene info

• Identity
  HGNC:33010
• Gene
  SNORD114-22
• Long gene name
  small nucleolar RNA, C/D box 114-22
• Synonyms
  • 14q(II-22)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767600
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003215.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:37616
• Gene
  PIRC112
• Long gene name
  piwi-interacting RNA cluster 112
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313803
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37615
• Gene
  PIRC111
• Long gene name
  piwi-interacting RNA cluster 111
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313937
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37612
• Gene
  PIRC108
• Long gene name
  piwi-interacting RNA cluster 108
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313878
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37613
• Gene
  PIRC109
• Long gene name
  piwi-interacting RNA cluster 109
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313913
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37437
• Gene
  VN1R112P
• Long gene name
  vomeronasal 1 receptor 112 pseudogene
• Locus
  22
• Discovery year
  2009-10-06
• Entrez gene record
  100312854
• RefSeq identity
  • NG_015712
• Classification
  • Vomeronasal receptors

Gene info

• Identity
  HGNC:37611
• Gene
  PIRC107
• Long gene name
  piwi-interacting RNA cluster 107
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313802
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37614
• Gene
  PIRC110
• Long gene name
  piwi-interacting RNA cluster 110
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313879
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37610
• Gene
  PIRC106
• Long gene name
  piwi-interacting RNA cluster 106
• Locus
  22
• Discovery year
  2009-11-05
• Entrez gene record
  100313877
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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