C-1 Esterase Inhibitor, Human Plasma

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:6204
Gene

JUN
Long gene name

Jun proto-oncogene, AP-1 transcription factor subunit
Synonyms gene name
- v-jun avian sarcoma virus 17 oncogene homolog
- jun oncogene
Synonyms
- c-Jun
- AP-1
GenBank acession
- AY217548
Locus

1p32.1
Discovery year

1988-05-11
Entrez gene record

3725
Pubmed identfication
- 3194415
RefSeq identity
- NM_002228
Classification
- Basic leucine zipper proteins
- Jun transcription factor family
VEGA ID

OTTHUMG00000008376

Identity

HGNC:3796
Gene

FOS
Long gene name

Fos proto-oncogene, AP-1 transcription factor subunit
Synonyms gene name
- v-fos FBJ murine osteosarcoma viral oncogene homolog
- FBJ murine osteosarcoma viral oncogene homolog
Synonyms
- c-fos
- AP-1
GenBank acession
- K00650
Locus

14q24.3
Discovery year

2001-06-22
Entrez gene record

2353
Pubmed identfication
RefSeq identity
- NM_005252
Classification
- Fos transcription factor family
- Basic leucine zipper proteins
VEGA ID

OTTHUMG00000171774

Identity

HGNC:10261
Gene

ROS1
Long gene name

ROS proto-oncogene 1, receptor tyrosine kinase
Synonyms gene name
- v-ros avian UR2 sarcoma virus oncogene homolog 1
- v-ros UR2 sarcoma virus oncogene homolog 1 (avian)
- c-ros oncogene 1 , receptor tyrosine kinase
Synonyms
- MCF3
- ROS
- c-ros-1
GenBank acession
- M13599
Locus

6q22.1
Discovery year

1986-01-01
Entrez gene record

6098
Pubmed identfication
- 1611909
Classification
- Receptor tyrosine kinases
- Fibronectin type III domain containing
VEGA ID

OTTHUMG00000016188
Locus Specific Databases
- LRG_997

Identity

HGNC:14013
Gene

SMC4
Long gene name

structural maintenance of chromosomes 4
Synonyms gene
- SMC4L1
Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
Synonyms
- hCAP-C
- CAP-C
GenBank acession
- AF092564
Locus

3q25.33
Discovery year

2001-02-22
Entrez gene record

10051
Pubmed identfication
- 9789013
- 10319587
Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000159006