Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
This is a highly specific antibody against LAT Tyr161.
1ug per 1ul
KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161
Gene ID Number
Human, Mouse, Rat
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen
Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Purified by Protein A.
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
LAT1; pp36; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; p36-38; LAT
Immunoglobulin G (IgG)
Alternative to gene target
linker for activation of T cells, LAT and IDBG-239499 and ENSG00000213658 and 27040, protein kinase binding, Cell surfaces, Lat and IDBG-209436 and ENSMUSG00000030742 and 16797, BT.26847 and IDBG-638875 and ENSBTAG00000021249 and 514735