Cathepsin C/DPP1 Antibody

• Catalog number
  bs-2672R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Cathepsin C/DPP1 Primary Polyclonal Antibody
• Also known as
  Cathepsin C/DPP1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Cathepsin C/DPP1
• Specificity
  This is a highly specific antibody against Cathepsin C/DPP1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DPP-I
• Gene ID number
  1075
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Dipeptidyl peptidase I; AI047818; CATC; Cathepsin C; Cathepsin J; CPPI; CTSC; Dipeptidyl peptidase 1; Dipeptidyl transferase; DPP I; DPPI; EC 3.4.14.1; HMS; JP; JPD; MGC126959; PALS; PLS.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
• French translation
  anticorps

• Gene target
  Cathepsin   C/DPP1  
• Gene symbol
  CTSC
• Short name
  Anti-Cathepsin C/DPP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Cathepsin C/DPP1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2528
• Gene
  CTSC
• Long gene name
  cathepsin C
• Synonyms gene
  • PLS
  • PALS
• Synonyms
  • DPP1
• Synonyms name
  • dipeptidyl peptidase 1
• GenBank acession
  • AK223038
• Locus
  11q14.2
• Discovery year
  1995-11-08
• Entrez gene record
  1075
• Pubmed identfication
  • 7649281
  • 9092576
• RefSeq identity
  • NM_001814
• Classification
  • Cathepsins
• VEGA ID
  OTTHUMG00000167290
• Locus Specific Databases
  • CTSCbase: Mutation registry for Papillon-Lefevre syndrome
  • LRG_50

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products