Phospho-LCK (Tyr394) Monoclonal Antibody

• Catalog number
  A1027-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Lck
• Target Alternative Name
  LCK , p56-LCK , p56lck , YT16 , pp58lck , LSK
• Antibody Type
  Monoclonal
• Clone
  5C6
• Species Reactivities
  Human
• Accession
  P06239
• Gene Id
  3932
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  100 ug (1 mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide.
• Purification
  Affinity purified mouse IgG using protein G
• Application
  Western blot, Immunoprecipitation, ELISA
• Description
  Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in some murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas. Resting T cells contain high levels of the Lck protein and mRNA both of which decline upon activation of the T cells. These and other observations sμggest that alterations in Lck expression may contribute to the pathogenesis of some types of neoplastic disease.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  Phospho-LCK   Tyr394   Monoclonal  
• Gene symbol
  LCK
• Short name
  Phospho-LCK (Tyr394) Monoclonal Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Isotype
  Mouse IgG
• Alternative name
  phosphorilated-lymphocyte-specific protein tyrosine kinase (Tyr394) monoclonal (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  lymphocyte-specific protein tyrosine kinase, IMD22 and LSK and p56lck and pp58lck and YT16, LCK and IDBG-95667 and ENSG00000182866 and 3932, transferase activity, Cell surfaces, Lck and IDBG-191117 and ENSMUSG00000000409 and 16818, LCK and IDBG-644592 and ENSBTAG00000012695 and 508890

Gene info

• Identity
  HGNC:6524
• Gene
  LCK
• Long gene name
  LCK proto-oncogene, Src family tyrosine kinase
• Synonyms gene name
  • lymphocyte-specific protein tyrosine kinase
• GenBank acession
  • M36881
• Locus
  1p35.2
• Discovery year
  1986-01-01
• Entrez gene record
  3932
• Pubmed identfication
  • 2787474
• RefSeq identity
  • NM_005356
• Classification
  • Src family tyrosine kinases
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000007463
• Locus Specific Databases
  • LRG_153

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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